Giannini D D, Chan K K, Roberts J D
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4221-3. doi: 10.1073/pnas.71.10.4221.
Carbon-13 nuclear magnetic resonance spectra have been obtained for the coumarin-related compounds warfarin and phenprocoumon. The spectral assignments indicate that warfarin exists as a mixture of cyclic hemiketal diastereomers in dimethyl sulfoxide solution. The sodium salt of warfarin exists as the ringopen form in water solution.
已获得香豆素相关化合物华法林和苯丙香豆素的碳-13核磁共振谱。光谱归属表明,华法林在二甲基亚砜溶液中以环状半缩酮非对映异构体的混合物形式存在。华法林钠盐在水溶液中以开环形式存在。