Benedet J L, Turko M, Fairey R N, Boyes D A
Am J Obstet Gynecol. 1979 May 15;134(2):201-7. doi: 10.1016/0002-9378(79)90886-x.
Clinical data on 264 patients with squamous cell carcinoma of the vulva seen between 1938 and 1976 are reported. Two hundred and four patients were "eligible" for 5 year assessment for a 55% survival rate. Patients treated with radical vulvectomy and bilateral lymphadenectomy had a corrected 5 year survival rate of 86% if the lymph nodes failed to show metastatic disease. Twenty-eight percent of the patients treated with lymphadenectomy had lymph node metastasis at the time of surgery. The presence of lymphatic metastasis appeared to be the most significant prognostic factor. The results obtained have led to a degree of individualization in current treatment policies, together with a re-evaluation of the possible role of radiotherapy.
报告了1938年至1976年间所见的264例外阴鳞状细胞癌患者的临床数据。204例患者“符合条件”进行5年评估，生存率为55%。如果淋巴结未显示转移疾病，接受根治性外阴切除术和双侧淋巴结切除术的患者校正后5年生存率为86%。接受淋巴结切除术的患者中有28%在手术时出现淋巴结转移。淋巴转移的存在似乎是最重要的预后因素。所获得的结果导致了当前治疗策略的一定程度的个体化，同时重新评估了放疗的可能作用。
