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血沉棕黄层白细胞聚集。一种简单、灵敏的细胞介导免疫测定法。

Aggregation of buffy-coat leucocytes. A simple, sensitive assay for cell-mediated immunity.

作者信息

Nicholls E M

出版信息

Clin Exp Immunol. 1974 Aug;17(4):673-80.

PMID:4534170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1554097/
Abstract

The addition of Tuberculin PPD to whole blood resulted in aggregation of the leucocytes. The degree of aggregation was assessed macroscopically and by two microscopic methods. The dose of PPD required to produce aggregation varied greatly between different subjects and an inverse correlation was noted between the dose of PPD needed and the Mantoux reaction.

摘要

将结核菌素纯蛋白衍生物（PPD）加入全血会导致白细胞聚集。通过肉眼观察和两种显微镜方法评估聚集程度。不同受试者产生聚集所需的PPD剂量差异很大，并且观察到所需PPD剂量与结核菌素皮肤试验反应呈负相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/fc7ec00898f9/clinexpimmunol00273-0145-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/99d4ceb3b895/clinexpimmunol00273-0144-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/41fe18d7f124/clinexpimmunol00273-0144-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/fc7ec00898f9/clinexpimmunol00273-0145-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/99d4ceb3b895/clinexpimmunol00273-0144-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/41fe18d7f124/clinexpimmunol00273-0144-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51dc/1554097/fc7ec00898f9/clinexpimmunol00273-0145-a.jpg

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Aggregation of buffy-coat leucocytes. A simple, sensitive assay for cell-mediated immunity.血沉棕黄层白细胞聚集。一种简单、灵敏的细胞介导免疫测定法。
Clin Exp Immunol. 1974 Aug;17(4):673-80.
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引用本文的文献

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2
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本文引用的文献

1
THE FATE OF PERITONEAL MACROPHAGES AFTER THE INJECTION OF ANTIGEN INTO GUINEA PIGS WITH DELAYED-TYPE HYPERSENSITIVITY.向患有迟发型超敏反应的豚鼠注射抗原后腹膜巨噬细胞的命运
Lab Invest. 1965 Jan;14:89-101.
2
DELAYED HYPERSENSITIVITY IN VITRO. I. THE SPECIFICITY OF INHIBITION OF CELL MIGRATION BY ANTIGENS.体外迟发型超敏反应。I. 抗原对细胞迁移抑制作用的特异性。
J Immunol. 1964 Aug;93:264-73.
3
The macrophage aggregation assay for delayed hypersensitivity: development of the response, role of the macrophage, and the independence of humoral antibody.
Clin Exp Immunol. 1976 Dec;26(3):528-30.
4
Leucocyte aggregation and lymphocyte transformation induced by mercuric chloride.氯化汞诱导的白细胞聚集和淋巴细胞转化
Clin Exp Immunol. 1976 Dec;26(3):531-3.
5
Immunologically mediated macrophage aggregation in monolayers of peritoneal cells from BCG-sensitized mice.卡介苗致敏小鼠腹膜细胞单层中免疫介导的巨噬细胞聚集。
Immunology. 1977 Jan;32(1):33-41.
迟发型超敏反应的巨噬细胞聚集试验：反应的发展、巨噬细胞的作用及体液抗体的独立性
Cell Immunol. 1972 Jan;3(1):53-61. doi: 10.1016/0008-8749(72)90225-0.
4
Management of adult acute myelogenous leukaemia.成人急性髓细胞白血病的管理
Br Med J. 1973 Jan 20;1(5846):131-7. doi: 10.1136/bmj.1.5846.131.
5
The production by antigen-stimulated lymphocytes of a leukotactic factor distinct from migration inhibitory factor.抗原刺激的淋巴细胞产生一种不同于迁移抑制因子的白细胞趋化因子。
Cell Immunol. 1970 Jul;1(2):162-74. doi: 10.1016/0008-8749(70)90003-1.