Cream J J
Clin Exp Immunol. 1972 Jan;10(1):117-26.
Serum cryoglobulin levels were estimated in thirty-one patients with cutaneous vasculitis, twenty-nine patients with other skin disorders and forty-seven normal subjects. Eighteen of the normal sera contained mixed cryoglobulins—the upper limit of the normal range being 80 μg/ml. Twelve of the vasculitis patients had serum cryoglobulin levels above the normal range. All but one of these cryoglobulins were mixed cryoglobulins. A low serum C3 level was found in only one patient. The possible role of mixed cryoglobulins in the pathogenesis of vasculitis is discussed.
对31例皮肤血管炎患者、29例其他皮肤病患者和47名正常受试者的血清冷球蛋白水平进行了评估。18份正常血清含有混合冷球蛋白,正常范围上限为80μg/ml。12例血管炎患者的血清冷球蛋白水平高于正常范围。除1例外,所有这些冷球蛋白均为混合冷球蛋白。仅1例患者血清C3水平较低。讨论了混合冷球蛋白在血管炎发病机制中的可能作用。