Möller B, Ringqvist C
Ann Clin Res. 1979 Feb;11(1):34-41.
Twenty one patients with either paroxysmal supraventricular tachycardia (group A), atrial flutter (group B), or atrial fibrillation (group C) were treated with intravenous metoprolol in the dose range 2--20 mg. Sinus rhythm was restored in 3 out of 6 patients in group A, 3 out of 7 patients in group B and one out of 8 patients in group C. In patients who did not convert to sinus rhythm a remarkable decrease in ventricular rate occurred in 3 patients with atrial flutter and 4 patients with atrial fibrillation. In patients with systolic blood pressure greater than 100 mm Hg but without an acute myocardial infarction the risk of hypotension necessitating treatment was small. Metoprolol appears to be an effective and safe drug in the treatment of supraventricular tachycardia.
21例阵发性室上性心动过速患者（A组）、心房扑动患者（B组）或心房颤动患者（C组）接受了剂量范围为2至20毫克的静脉注射美托洛尔治疗。A组6例患者中有3例恢复窦性心律，B组7例患者中有3例恢复窦性心律，C组8例患者中有1例恢复窦性心律。未转为窦性心律的患者中，3例心房扑动患者和4例心房颤动患者的心室率显著降低。收缩压高于100毫米汞柱但无急性心肌梗死的患者发生需治疗的低血压风险较小。美托洛尔似乎是治疗室上性心动过速的一种有效且安全的药物。
