Horwitz O, Bunch-Christensen K
Bull World Health Organ. 1972;47(1):49-58.
A study was made of the responses of schoolchildren to tuberculin testing 2 months and 5 years after vaccination with one of 11 different BCG vaccines prepared by several laboratories from different strains. The fact that the allergenic response was almost unchanged after 5 years shows that a long-term follow-up adds nothing of any significance to the information obtained 2 months after vaccination. The study also showed that postvaccinal tuberculin testing is only of value in determining the level of the allergy in groups of persons. It yields little information on the level in individuals since several factors, including unavoidable experimental errors and unknown personal factors, greatly influence the reaction.
对学童接种由几个实验室从不同菌株制备的11种不同卡介苗疫苗之一后2个月和5年的结核菌素试验反应进行了研究。5年后过敏反应几乎没有变化这一事实表明,长期随访对接种疫苗2个月后获得的信息没有增加任何有意义的内容。该研究还表明,接种疫苗后的结核菌素试验仅在确定人群过敏水平方面有价值。由于包括不可避免的实验误差和未知个人因素在内的几个因素对反应有很大影响,它几乎无法提供关于个体水平的信息。