新城疫病毒和风疹病毒在类风湿性和非类风湿性滑膜细胞培养物中的生长情况。
Growth of Newcastle disease virus and rubella virus in rheumatoid and nonrehumatoid synovial cell cultures.
作者信息
Spruance S L, Smith C B, Krall J, Ward J R
出版信息
Infect Immun. 1972 Sep;6(3):326-9. doi: 10.1128/iai.6.3.326-329.1972.
Abstract
Rheumatoid and nonrheumatoid synovial cell cultures were challenged with Newcastle disease virus and rubella virus in an attempt to confirm reports that rheumatoid synovial cells are relatively resistant to infection with these viruses. Newcastle disease virus caused complete cell destruction by day 7 in both rheumatoid and nonrheumatoid cultures, and peak virus titers were similar. Rubella virus replicated in both rheumatoid and nonrheumatoid synovial cell cultures, and no consistent differences in virus titers were detected. Rubella-infected cell lines were observed for up to 28 days and no virus-specific cytopathic effect was seen.
摘要
用新城疫病毒和风疹病毒对类风湿性和非类风湿性滑膜细胞培养物进行攻击，以试图证实有关类风湿性滑膜细胞对这些病毒感染具有相对抗性的报道。在类风湿性和非类风湿性培养物中，新城疫病毒在第7天时导致细胞完全破坏，且病毒滴度峰值相似。风疹病毒在类风湿性和非类风湿性滑膜细胞培养物中均能复制，未检测到病毒滴度的一致差异。对风疹感染的细胞系观察长达28天，未发现病毒特异性细胞病变效应。
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本文引用的文献
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