Sabour M S, el-Said W, Abou-Gabal I
Bull World Health Organ. 1972;47(5):549-57.
In a Cairo clinic 17 of 41 patients with chronic pyelonephritis secondary to urinary schistosomiasis presented with classical features of the nephrotic syndrome, two-thirds being hypertensive and the majority having glomerular filtration rates within the normal range. Hypercholesterolaemia was found in one-third of the patients. Urinary sediments from these patients contained a preponderance of pus cells, red cells, granular casts, or pus casts. In addition to patches of pyelonephritis, the glomeruli showed diffuse and focal glomerulosclerosis. Electron microscopy revealed basement-membrane-like deposits in the hypertrophied axial endothelial cells and electron-dense deposits along the glomerular basement membrane. This variety of nephrotic syndrome associated with schistosomal pyelonephritis was the most common cause of nephrotic syndrome seen in the clinic.
在开罗的一家诊所，41例血吸虫病继发慢性肾盂肾炎患者中有17例表现出典型的肾病综合征特征，其中三分之二患有高血压，大多数患者的肾小球滤过率在正常范围内。三分之一的患者存在高胆固醇血症。这些患者的尿沉渣中以脓细胞、红细胞、颗粒管型或脓细胞管型为主。除了肾盂肾炎病灶外，肾小球还表现为弥漫性和局灶性肾小球硬化。电子显微镜检查显示，肥大的轴突内皮细胞中有基底膜样沉积物，沿肾小球基底膜有电子致密沉积物。这种与血吸虫性肾盂肾炎相关的肾病综合征是该诊所中肾病综合征最常见的病因。
