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苏丹的肾病综合征,特别提及血吸虫性肾病。一项初步形态学研究。

The nephrotic syndrome in the Sudan with special reference to schistosomal nephropathy. A preliminary morphological study.

作者信息

Veress B, Musa A R, Osman H, Asha A, Saddig E W, El Hassan A M

出版信息

Ann Trop Med Parasitol. 1978 Aug;72(4):357-61. doi: 10.1080/00034983.1978.11719329.

Abstract

The morphology of 68 renal biopsies from the Sudan is analysed. Schistosomal infection was more common among the nephrotic patients than in the average population (32% against less than 1%). In the schistosomal group the high incidence of focal sclerosing glomerulonephritis (28%) and of secondary amyloidosis (38%) was remarkable. The history is described of a boy in whom repeated biopsies showed the decrease of glomerular amyloid depositions accompanied by mesangial cell proliferation following treatment for schistosomiasis.

摘要

对来自苏丹的68份肾活检样本的形态学进行了分析。血吸虫感染在肾病患者中比在普通人群中更为常见(32% 对比不到1%)。在血吸虫病组中,局灶性硬化性肾小球肾炎(28%)和继发性淀粉样变性(38%)的高发病率很显著。描述了一名男孩的病史,其反复活检显示,在接受血吸虫病治疗后,肾小球淀粉样沉积物减少,同时伴有系膜细胞增殖。

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