Lund M
Bull World Health Organ. 1972;47(5):611-8.
Inherited resistance to anticoagulant rodenticides was discovered in populations of Rattus norvegicus about 14 years ago. Similar resistance has now been reported from several countries in north-western Europe and from the USA. In order to detect resistance and to control it effectively, basic data on the susceptibility of rat populations are required for each country, and trapping surveys should be made in any area where resistance is suspected. Acute poisons are needed to control resistant rats although the shift from anticoagulants to acute poisons is a retrograde step as far as efficiency is concerned, and increases the hazard of control operations to man and other animals. Resistance to anticoagulants in Mus musculus has been reported from England, and resistant mice are probably to be found in other countries also in view of the great individual variation in susceptibility of this species to these rodenticides.
大约14年前，在褐家鼠种群中发现了对抗凝血灭鼠剂的遗传性抗性。现在，西北欧的几个国家以及美国都报告了类似的抗性情况。为了检测抗性并有效控制它，每个国家都需要有关大鼠种群易感性的基础数据，并且在任何怀疑有抗性的地区都应进行诱捕调查。虽然从抗凝血剂转向急性毒药在效率方面是一个倒退的步骤，并且增加了控制行动对人类和其他动物的危害，但仍需要急性毒药来控制抗性大鼠。英国已报告小家鼠对抗凝血剂有抗性，鉴于该物种对这些灭鼠剂的易感性存在很大的个体差异，其他国家可能也存在抗性小鼠。
