Boling M E, Allison D P, Setlow J K
J Virol. 1973 Apr;11(4):585-91. doi: 10.1128/JVI.11.4.585-591.1973.
The phages HP1c1 and S2 and a defective phage of Haemophilus influenzae have been compared. The morphology of the phages and the mol wt of their DNAs are similar, although the defective phage appears to have a different tail plate region. Electron microscope observation indicates that the defective phage does not attach to the cell surface, and its DNA appears to lack cohesive ends. The homology of the DNAs of the phages has been measured by hydridization. DNA from the defective phage shows little or no homology with the other phage DNAs. HP1c1 and S2 DNAs show a high level of homology. Each of these phages can form plaques on lawns of the lysogen of the other phage but at reduced plating efficiencies, suggesting that the two phages have related but not identical immunity systems.
已对噬菌体HP1c1和S2以及流感嗜血杆菌的一种缺陷噬菌体进行了比较。尽管缺陷噬菌体的尾板区域似乎有所不同，但这些噬菌体的形态及其DNA的分子量相似。电子显微镜观察表明，缺陷噬菌体不附着于细胞表面，并且其DNA似乎缺乏粘性末端。已通过杂交测定了噬菌体DNA的同源性。缺陷噬菌体的DNA与其他噬菌体DNA几乎没有同源性或完全没有同源性。HP1c1和S2的DNA显示出高度同源性。这些噬菌体中的每一种都可以在另一种噬菌体的溶原菌菌苔上形成噬菌斑，但平板接种效率降低，这表明这两种噬菌体具有相关但不相同的免疫体系。
