Nikitin A, Cohen D, Todd J D, Lief F S
Bull World Health Organ. 1972;47(4):471-9.
Experimental inoculation of dogs with the A/Hong Kong/68 influenzavirus resulted in subclinical infection. The virus was readily passed to contacts in the same cage when the latter were exposed in the same inoculation room 24 hours after experimental infection. Removing the site of contact to a noncontaminated room or delaying contact until 48 hours after experimental inoculation greatly reduced the possibility of infection in contact animals. A survey of 271 canine serum samples obtained after a human epidemic from different geographical areas of the USA and the United Kingdom showed that 5.9% of the samples were positive; no positive reactions were found among 111 pre-epidemic samples. These studies demonstrated the laboratory and natural susceptibility of dogs to the Hong Kong variant and suggest the possible role of dogs in the epidemiology of human influenza.
用A/香港/68流感病毒对犬进行实验性接种导致亚临床感染。当实验感染24小时后，将同一笼子里的接触动物置于同一接种室时，病毒很容易传播给它们。将接触场所转移到未受污染的房间或在实验接种48小时后再进行接触，可大大降低接触动物感染的可能性。对美国和英国不同地理区域在一次人类流感流行后采集的271份犬血清样本进行的调查显示，5.9%的样本呈阳性；在111份流行前样本中未发现阳性反应。这些研究证明了犬对香港变种的实验室易感性和自然易感性，并提示犬在人类流感流行病学中可能发挥的作用。
