Frick M H, Harjola P T, Valle M
Clin Cardiol. 1979 Apr;2(2):81-6. doi: 10.1002/clc.4960020201.
Exercise tolerance was repeatedly determined over a 2-year period in a series of 100 patients with coronary heart disease randomly allocated for medical therapy and coronary bypass surgery. The surgical group had a consistently better exercise tolerance than the medical group during the whole follow-up. Completeness of the revascularization, assessed by repeated graft and native vessel angiography, resulted in a marked improvement whereas incompletely revascularized patients exhibited only a marginal improvement which, nevertheless, to some degree exceeded the result of medical management alone. It is concluded that coronary bypass surgery and medical therapy, when indicated, result in markedly better exercise tolerance than medical management alone. This improvement persists up two years after the operation and is largely dependent on the completeness of the revascularization.
在为期两年的时间里，对100例冠心病患者进行了反复的运动耐量测定，这些患者被随机分配接受药物治疗和冠状动脉搭桥手术。在整个随访期间，手术组的运动耐量始终优于药物组。通过反复的移植血管和自身血管造影评估的血运重建完整性带来了显著改善，而血运重建不完全的患者仅表现出轻微改善，不过，这种改善在一定程度上超过了单纯药物治疗的结果。得出的结论是，冠状动脉搭桥手术和药物治疗在有指征时，比单纯药物治疗能带来明显更好的运动耐量。这种改善在手术后持续两年，并且很大程度上取决于血运重建的完整性。
