Dizadji H, Hammer R, Strzyz B, Weisenberger J
Arch Surg. 1979 Jun;114(6):734-5. doi: 10.1001/archsurg.1979.01370300088017.
Therapeutic doses of oral anticoagulants have been associated with spontaneous hemorrhage and rupture of apparently normal abdominal viscera. To our knowledge, this is the second reported case of such rupture involving the liver. The patient had sudden severe epigastric pain and signs of acute abdomen and shock. Discrete microscopic changes in the liver may precede massive hemorrhage.
口服抗凝剂的治疗剂量与明显正常的腹部脏器自发性出血和破裂有关。据我们所知，这是第二例有报道的涉及肝脏的此类破裂病例。该患者突发严重上腹部疼痛，伴有急腹症和休克体征。肝脏中离散的微观变化可能先于大量出血出现。
