Wong K P, Gillett P G
Can Med Assoc J. 1977 Feb 19;116(4):388-90.
A 43-year old woman had recurrent massive intraperitoneal hemorrhage from rupture of a hemorrhagic corpus luteum in two successive menstrual cycles while receiving anticoagulant therapy. Left oophorectomy was performed on the first occasion and right salpingo-oophorectomy with left salpingectomy on the second. While the precise incidence cannot be determined, rupture from a hemorrhagic corpus luteum appears to be a rare but potentially catastrophic complication of anticoagulant therapy. Hence possible ovarian hemorrhage should be considered in women of reproductive age receiving heparin or sodium warfarin therapy.
一名43岁女性在接受抗凝治疗期间，连续两个月经周期出现黄体破裂导致反复大量腹腔内出血。首次发作时进行了左侧卵巢切除术，第二次进行了右侧输卵管卵巢切除术并切除了左侧输卵管。虽然确切发病率尚无法确定，但黄体破裂似乎是抗凝治疗罕见但可能灾难性的并发症。因此，接受肝素或华法林钠治疗的育龄女性应考虑可能的卵巢出血。
