Mulley J C, James J W, Barker J S
Biochem Genet. 1979 Feb;17(1-2):105-26. doi: 10.1007/BF00484477.
Allozyme frequency data from natural populations of Drosophila buzzatii were analyzed for genotype--environment relationships. Allele frequency and heterozygosity at six loci polymorphic throughout eastern Australia and a number of environmental factors (both means and variabilities) were examined by a variety of multivariate techniques. Significant genotype--environment associations were found for five of the six loci, and after correcting for geographic location significant associations remained for Est-2 and Adh-1 gene frequencies and heterozygosities and for Pgm gene frequencies. The results are discussed in relation to selection and gene flow and provide the basis for laboratory studies to disentangle confounded effects of (1) environmental means and environmental variabilities and (2) allele frequency and heterozygosity, and thus to further test for and determine the nature of any natural selection at particular allozyme loci.
对果蝇自然种群的等位酶频率数据进行了分析，以研究基因型与环境的关系。通过多种多变量技术，研究了澳大利亚东部六个多态位点的等位基因频率和杂合性以及一些环境因素（均值和变异性）。六个位点中的五个发现了显著的基因型与环境关联，在校正地理位置后，Est-2和Adh-1基因频率及杂合性以及Pgm基因频率仍存在显著关联。讨论了这些结果与选择和基因流的关系，并为实验室研究提供了基础，以厘清（1）环境均值和环境变异性以及（2）等位基因频率和杂合性的混杂效应，从而进一步测试并确定特定等位酶位点上自然选择的性质。
