Cooke P H, Barker J S, East P D
Heredity (Edinb). 1986 Aug;57 ( Pt 1):47-51. doi: 10.1038/hdy.1986.85.
Genotype frequencies at the alcohol dehydrogenase-1 (Adh-1) locus of D. buzzatii were analysed for deviations from Hardy-Weinberg equilibria in the progeny of laboratory populations established at five initial Adh-1b allele frequencies and kept at either 18 degrees C, 25 degrees C or 30 degrees C. At 25 degrees C, no observed genotype frequencies were significantly different from Hardy-Weinberg expectations. Observed frequencies of heterozygotes were generally less than expected for populations at 18 degrees C and 30 degrees C. Fitness differences among genotypes were greater in males than in females, with Adh-1b homozygotes having highest fitness at 18 degrees C and Adh-1c homozygotes having highest fitness at 30 degrees C. The results are discussed in relation to previous field and laboratory studies on D. buzzatii and to the Adh polymorphism of D. melanogaster.
对巴氏果蝇乙醇脱氢酶-1(Adh-1)位点的基因型频率进行了分析,以研究在五个初始Adh-1b等位基因频率下建立的实验室种群后代中,其基因型频率是否偏离哈迪-温伯格平衡,这些种群分别饲养在18摄氏度、25摄氏度或30摄氏度的环境中。在25摄氏度时,观察到的基因型频率与哈迪-温伯格预期值没有显著差异。在18摄氏度和30摄氏度时,杂合子的观察频率通常低于种群预期值。雄性基因型之间的适合度差异大于雌性,在18摄氏度时,Adh-1b纯合子具有最高适合度,在30摄氏度时,Adh-1c纯合子具有最高适合度。本文结合先前关于巴氏果蝇的野外和实验室研究以及黑腹果蝇的Adh多态性对结果进行了讨论。