体外通过多聚腺苷酸：多聚尿苷酸和多聚肌苷酸：多聚胞苷酸刺激B细胞。
Stimulation of B cells by poly A: poly U and poly I: poly C in vitro.
作者信息
Rühl H, Vogt W, Bochert G, Diamantstein T
出版信息
Immunology. 1974 May;26(5):937-41.
Abstract
Both poly I:poly C and poly A:poly U stimulate [H]thymidine incorporation by spleen cells derived from normal or from cortisone-treated mice. The highest rate of stimulation was detected in the spleen cells of nude mice. Compared with spleen cells, thymus cells and cortisone-resistant thymus cells gave only a small but reproducible response. The results suggest that double-stranded polynucleotides act preferentially on B cells in the same way as dextran sulphate.
摘要
聚肌苷酸
聚胞苷酸和聚腺苷酸:聚尿苷酸均能刺激来自正常小鼠或经可的松处理的小鼠的脾细胞掺入[H]胸腺嘧啶核苷。在裸鼠的脾细胞中检测到最高的刺激率。与脾细胞相比，胸腺细胞和可的松抗性胸腺细胞仅产生小但可重复的反应。结果表明，双链多核苷酸与硫酸葡聚糖一样，优先作用于B细胞。
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