Vischer T L
Agents Actions. 1976 Jul;6(4):479-82. doi: 10.1007/BF01973263.
Suramin, a drug against trypanosomiasis and onchocerciasis, stimulates in vitro mouse B-lymphocytes to transform into blastcells, to incorporate 3H-thymidine and to go into mitosis. Thymus cells (hydro-cortisone-sensitive or resistant) do not respond whereas cells from homozygous nude mice are stimulated. The large majority of the blast-cells have surface immunoglobulins, and the proportion of cells with intracellular immunoglobulin increases during the course of the cultures.
苏拉明是一种治疗锥虫病和盘尾丝虫病的药物，它能在体外刺激小鼠B淋巴细胞转化为母细胞，掺入3H-胸腺嘧啶核苷并进入有丝分裂。胸腺细胞（对氢化可的松敏感或耐药）无反应，而纯合裸鼠的细胞则受到刺激。绝大多数母细胞具有表面免疫球蛋白，并且在培养过程中细胞内免疫球蛋白的细胞比例增加。
