Lorber J, Bhat U S
Arch Dis Child. 1974 Oct;49(10):751-62. doi: 10.1136/adc.49.10.751.
The clinical features, investigations, and results of treatment are described in a series of 47 infants with posthaemorrhagic hydrocephalus. 7 were unfit for treatment; 3 had medical (isosorbide) treatment alone, 2 of whom made a good recovery; the remaining 37 were surgically treated. 32 (68%) survived for 18 months to 16 years, but 12 of them are severely affected mentally and/or physically. The results can be considered satisfactory in 19 (40%), though there are only 9 (19%) without detectable sequelae. The most serious adverse prognostic features on admission were acute illness with active bleeding or neurological signs such as spasticity, fits, visual defects, or subdural effusions, and such infants did not recover without severe sequelae. The degree of hydrocephalus was also of prognostic value. Since results could have been far better with better management, it is hoped that the publication of this series will lead to better care and prognosis.
本文描述了47例出血后脑积水婴儿的临床特征、检查及治疗结果。7例不适合治疗；3例仅接受药物（异山梨醇）治疗，其中2例恢复良好；其余37例接受了手术治疗。32例（68%）存活18个月至16年，但其中12例存在严重的智力和/或身体障碍。19例（40%）的结果可认为是令人满意的，不过只有9例（19%）没有可检测到的后遗症。入院时最严重的不良预后特征是伴有活动性出血的急性疾病或诸如痉挛、惊厥、视力缺陷或硬膜下积液等神经体征，这类婴儿若无严重后遗症则无法恢复。脑积水的程度也具有预后价值。鉴于更好的管理可能会带来更好的结果，希望本系列病例的发表能带来更好的护理和预后。
