In vitro spleen leucocyte migration and phytohaemagglutinin-stimulated lymphocyte transformation of immunosuppressed mice cells. II. Cells from mice treated by azathioprine and/or immune stimulation or thymectomy.
作者信息
House A K, Boak J L, Draper V
出版信息
Clin Exp Immunol. 1974 May;17(1):189-98.
Abstract
An study of the spleen leucocyte migration ability and the phytohaemag-glutinin (PHA) stimulated peripheral lymphocyte response was made on cells derived from mice treated by azathioprine, immune stimulation, or thymectomy and azathioprine. These responses were compared with those shown by normal mice and found to be considerably depressed. Thymectomy combined with azathioprine produced the greatest change which persisted at 40 days. These changes suggested that azathioprine in common with thymectomy, antilymphocyte globulin and radiotherapy produced some of its immunosuppression by depressing T-cell function.
摘要
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In vitro spleen leucocyte migration and phytohaemagglutinin-stimulated lymphocyte transformation of immunosuppressed mice cells. I. Cells from mice treated by thymectomy and/or rabbit anti-mouse lymphocyte serum.免疫抑制小鼠细胞的体外脾白细胞迁移及植物血凝素刺激的淋巴细胞转化。I. 经胸腺切除和/或兔抗小鼠淋巴细胞血清处理的小鼠细胞。
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In vitro spleen leucocyte migration and phytohaemagglutinin-stimulated lymphocyte transformation of immunosuppressed mice cells. I. Cells from mice treated by thymectomy and/or rabbit anti-mouse lymphocyte serum.免疫抑制小鼠细胞的体外脾白细胞迁移及植物血凝素刺激的淋巴细胞转化。I. 经胸腺切除和/或兔抗小鼠淋巴细胞血清处理的小鼠细胞。
Clin Exp Immunol. 1974 May;17(1):179-87.
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