免疫抑制小鼠细胞的体外脾白细胞迁移及植物血凝素刺激的淋巴细胞转化。I. 经胸腺切除和/或兔抗小鼠淋巴细胞血清处理的小鼠细胞。
In vitro spleen leucocyte migration and phytohaemagglutinin-stimulated lymphocyte transformation of immunosuppressed mice cells. I. Cells from mice treated by thymectomy and/or rabbit anti-mouse lymphocyte serum.
作者信息
House A K, Boak J L, Draper V
出版信息
Clin Exp Immunol. 1974 May;17(1):179-87.
Abstract
An study of spleen leucocyte migration ability and phytohaemagglutinin (PHA) stimulated peripheral lymphocyte transformation response was made on cells derived from mice treated by thymectomy, thymectomy and/or rabbit anti-mouse lymphocyte serum (RAMLS). These responses were compared with those shown by normal mice and found to be considerably depressed. Thymectomy combined with RAMLS treatment produced the greatest change. This decreased activity persisted for up to 100 days. The spleen leucocyte migration results changed in parallel with the PHA-stimulated lymphocyte response and were considered to reflect a T-cell function.
摘要
对经胸腺切除、胸腺切除和/或兔抗小鼠淋巴细胞血清（RAMLS）处理的小鼠来源的细胞进行了脾脏白细胞迁移能力和植物血凝素（PHA）刺激的外周淋巴细胞转化反应的研究。将这些反应与正常小鼠的反应进行比较，发现明显受到抑制。胸腺切除联合RAMLS处理产生的变化最大。这种活性降低持续长达100天。脾脏白细胞迁移结果与PHA刺激的淋巴细胞反应平行变化，被认为反映了T细胞功能。
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In vitro spleen leucocyte migration and phytohaemagglutinin-stimulated lymphocyte transformation of immunosuppressed mice cells. I. Cells from mice treated by thymectomy and/or rabbit anti-mouse lymphocyte serum.免疫抑制小鼠细胞的体外脾白细胞迁移及植物血凝素刺激的淋巴细胞转化。I. 经胸腺切除和/或兔抗小鼠淋巴细胞血清处理的小鼠细胞。
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引用本文的文献
1
In vitro spleen leucocyte migration and phytohaemagglutinin-stimulated lymphocyte transformation of immunosuppressed mice cells. II. Cells from mice treated by azathioprine and/or immune stimulation or thymectomy.免疫抑制小鼠细胞的体外脾白细胞迁移及植物血凝素刺激的淋巴细胞转化。II. 经硫唑嘌呤和/或免疫刺激或胸腺切除处理的小鼠细胞。
Clin Exp Immunol. 1974 May;17(1):189-98.
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