Mendelow A D, Karmi M Z, Paul K S, Fuller G A, Gillingham F J
Br Med J. 1979 May 12;1(6173):1240-2. doi: 10.1136/bmj.1.6173.1240.
The case records of patients with extradural haematomas treated in the Lothian region during 1951-60 and 1968-77 were analysed to assess the effect of delay in treatment on morbidity and mortality. Delay was defined as the time from deterioration in level of consciousness to surgical evacuation of clot. There were 83 supratentorial extradural haematomas unassociated with intradural clot or contusion. The mean delay in patients who died was 15.7 hours, while in good-quality survivors the mean delay was 1.9 hours. Mortality decreased from 33.3% during 1951-60 to 8.9% during 1968-77. In addition, good recovery without morbidity occurred in 40.7% of patients in the earlier period and 67.9% in the later period. Mean delays from deterioration in level of consciousness to operation were 9.8 and 2.4 hours in the earlier and later periods respectively. The results emphasise the need for immediate operation in patients deteriorating with extradural haematomas. Direct admission of all head-injured patients to a head and spinal injuries unit staffed by neurosurgeons resulted in minimal delay times as well as a reduction in morbidity and mortality.
对1951年至1960年以及1968年至1977年在洛锡安地区接受治疗的硬膜外血肿患者的病例记录进行了分析,以评估治疗延迟对发病率和死亡率的影响。延迟定义为从意识水平恶化到手术清除血凝块的时间。共有83例幕上硬膜外血肿,与硬膜内血凝块或挫伤无关。死亡患者的平均延迟时间为15.7小时,而恢复良好的幸存者的平均延迟时间为1.9小时。死亡率从1951年至1960年期间的33.3%降至1968年至1977年期间的8.9%。此外,早期40.7%的患者和后期67.9%的患者实现了无并发症的良好康复。从意识水平恶化到手术的平均延迟时间在早期和后期分别为9.8小时和2.4小时。结果强调了硬膜外血肿病情恶化患者需要立即手术。所有头部受伤患者直接入住由神经外科医生配备的头部和脊柱损伤病房,可将延迟时间降至最短,并降低发病率和死亡率。