Flear C T, Hilton P
Br Med J. 1979 May 12;1(6173):1242-6. doi: 10.1136/bmj.1.6173.1242.
A total of 235 consecutive patients admitted to a coronary care unit were investigated for serum electrolyte and urea concentrations; activities of aspartate amino-transferase, lactate dehydrogenase, and lactate dehydrogenase isoenzymes; electrocardiographic changes; clinical state; and outcome. Hyponatraemia, hypochloraemia, and uraemia were common in patients with confirmed myocardial infarctions, the degree of infarction correlating well with all the above indices of severity. The day-to-day variability of plasma sodium, chloride, and potassium concentrations was often increased above normal. Disturbances were greater in patients given diuretics. It is concluded that plasma sodium concentration fall after infarction and that the extent and duration of the fall are indices of the severity of the infarction.
对连续入住冠心病监护病房的235例患者进行了血清电解质和尿素浓度、天冬氨酸转氨酶、乳酸脱氢酶及其同工酶活性、心电图变化、临床状态及预后的调查。低钠血症、低氯血症和尿毒症在确诊心肌梗死患者中很常见，梗死程度与上述所有严重程度指标密切相关。血浆钠、氯和钾浓度的每日变化通常高于正常水平。使用利尿剂的患者干扰更大。结论是，梗死后血浆钠浓度下降，下降的程度和持续时间是梗死严重程度的指标。
