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相似文献

1
A ribosome dissociation factor from rabbit reticulocytes (fluoride-E. coli ribosomes-initiation factors).一种来自兔网织红细胞的核糖体解离因子（氟化物-大肠杆菌核糖体-起始因子）。
Proc Natl Acad Sci U S A. 1972 Feb;69(2):353-7. doi: 10.1073/pnas.69.2.353.
2
Preparation and assay of ribosome dissociation factors from Escherichia coli and rabbit reticulocytes and the assay for free ribosomes.大肠杆菌和兔网织红细胞核糖体解离因子的制备与测定以及游离核糖体的测定
Methods Enzymol. 1974;30:87-94. doi: 10.1016/0076-6879(74)30012-2.
3
Polypeptide chain initiation in eukaryotes: functional identity of supernatant factor from various sources.真核生物中的多肽链起始：不同来源上清因子的功能特性
Proc Natl Acad Sci U S A. 1972 Jul;69(7):1796-9. doi: 10.1073/pnas.69.7.1796.
4
Separation of reticulocyte initiation factor M 2 activity into two components.网织红细胞起始因子M2活性分离为两个组分。
Proc Natl Acad Sci U S A. 1972 Apr;69(4):983-7. doi: 10.1073/pnas.69.4.983.
5
Interaction of rabbit reticulocyte ribosomes with bacteriophage f1 mRNA and of Escherichia coli ribosomes with rabbit globin mRNA.兔网织红细胞核糖体与噬菌体f1信使核糖核酸以及大肠杆菌核糖体与兔珠蛋白信使核糖核酸之间的相互作用。
Proc Natl Acad Sci U S A. 1977 Jul;74(7):2692-6. doi: 10.1073/pnas.74.7.2692.
6
Two eukaryotic initiation factors (IF-I and IF-II) of protein synthesis that are required to form an initiation complex with rabbit reticulocyte ribosomes.两种蛋白质合成的真核起始因子（IF-I和IF-II），它们是与兔网织红细胞核糖体形成起始复合物所必需的。
Proc Natl Acad Sci U S A. 1974 Feb;71(2):436-40. doi: 10.1073/pnas.71.2.436.
7
Effect of puromycin and sodium fluoride on reticulocyte ribosomal monomers and subribosomal particles.嘌呤霉素和氟化钠对网织红细胞核糖体单体及核糖体亚基颗粒的影响。
Arch Biochem Biophys. 1968 May;125(2):449-51. doi: 10.1016/0003-9861(68)90601-2.
8
Migration of 40 S ribosomal subunits on messenger RNA when initiation is perturbed by lowering magnesium or adding drugs.
J Biol Chem. 1979 Jun 10;254(11):4731-8.
9
Re-activation of the peptidyltransferase centre of rabbit reticulocyte ribosomes after inactivation by exposure to low concentrations of magnesium ion.经低浓度镁离子处理而失活的兔网织红细胞核糖体肽基转移酶中心的重新激活。
Biochem J. 1976 Dec 15;160(3):521-31. doi: 10.1042/bj1600521.
10
Factor-promoted dissociation of free ribosomes in a rabbit reticulocyte lysate system: inhibition and requirement for an energy source.因子促进兔网织红细胞裂解液系统中游离核糖体的解离：对能量来源的抑制作用及需求
Proc Natl Acad Sci U S A. 1973 Mar;70(3):787-91. doi: 10.1073/pnas.70.3.787.

引用本文的文献

1
Influence of heating on the formation of ribosome couples and 80S initiation complex from the 40S and 60S ribosomal subunits from rabbit reticulocytes.加热对兔网织红细胞40S和60S核糖体亚基形成核糖体偶联物及80S起始复合物的影响。
Mol Gen Genet. 1974;128(2):171-82. doi: 10.1007/BF02654489.
2
Dietary protein intake and skeletal-muscle protein metabolism in rats. Studies with the ammonium chloride-wash fraction from crude polyribosomes of well-nourished and protein-depleted rats.大鼠的膳食蛋白质摄入量与骨骼肌蛋白质代谢。对营养良好和蛋白质缺乏大鼠粗多核糖体的氯化铵洗涤组分的研究。
Biochem J. 1973 Nov;136(3):773-80. doi: 10.1042/bj1360773.
3
A ribosome dissociation factor from rabbit reticulocytes distinct from initiation factor M3.一种来自兔网织红细胞的核糖体解离因子，与起始因子M3不同。
Proc Natl Acad Sci U S A. 1973 Aug;70(8):2220-3. doi: 10.1073/pnas.70.8.2220.
4
Use of purified polysomes from rabbit reticulocytes in a specific test for initiation factors.在一项针对起始因子的特定测试中使用来自兔网织红细胞的纯化多核糖体。
Proc Natl Acad Sci U S A. 1974 Jan;71(1):68-72. doi: 10.1073/pnas.71.1.68.
5
Factor-promoted dissociation of free ribosomes in a rabbit reticulocyte lysate system: inhibition and requirement for an energy source.因子促进兔网织红细胞裂解液系统中游离核糖体的解离：对能量来源的抑制作用及需求
Proc Natl Acad Sci U S A. 1973 Mar;70(3):787-91. doi: 10.1073/pnas.70.3.787.
6
Inhibition of cellular protein synthesis by double-stranded RNA: inactivation of an initiation factor.双链RNA对细胞蛋白质合成的抑制作用：一种起始因子的失活
Proc Natl Acad Sci U S A. 1973 Apr;70(4):1222-6. doi: 10.1073/pnas.70.4.1222.
7
Endogenous messenger ribonucleic acid-directed polypeptide chain elongation in a cell-free system from the yeast Saccharomyces cerevisiae.来自酿酒酵母的无细胞系统中内源性信使核糖核酸指导的多肽链延伸
J Bacteriol. 1975 May;122(2):719-26. doi: 10.1128/jb.122.2.719-726.1975.
8
Reassociation of eukaryotic ribosomal subunits by a factor from rat ascites hepatoma cytosol.大鼠腹水肝癌细胞溶质中的一种因子介导真核生物核糖体亚基的重新结合
Experientia. 1979 Oct 15;35(10):1305-6. doi: 10.1007/BF01963974.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The size and hydration of rabbit-reticulocyte ribosomes.兔网织红细胞核糖体的大小与水合作用
Biochim Biophys Acta. 1960 Jan 1;37:152-3. doi: 10.1016/0006-3002(60)90093-7.
3
Evidence for a naF-resistant association between mRNA and ribosomes in rabbit reticulocytes.家兔网织红细胞中mRNA与核糖体之间存在对新霉素不敏感关联的证据。
Biochim Biophys Acta. 1967 Mar 29;138(1):186-8. doi: 10.1016/0005-2787(67)90599-0.
4
Sedimentation studies on the interaction of ribosomal subunits from liver.肝脏核糖体亚基相互作用的沉降研究。
Biochim Biophys Acta. 1966 Sep;123(3):523-33. doi: 10.1016/0005-2787(66)90220-6.
5
Ribosomal subunit exchange in the cytoplasm of a eukaryote.真核生物细胞质中的核糖体亚基交换。
Nature. 1969 Jun 7;222(5197):950-3. doi: 10.1038/222950a0.
6
Initiation of protein synthesis in a rabbit reticulocyte lysate system.兔网织红细胞裂解液系统中蛋白质合成的起始
Biochim Biophys Acta. 1971 Jan 28;228(2):526-35. doi: 10.1016/0005-2787(71)90058-x.
7
Subunit recycling during translation in a reticulocyte cell-free system.
J Biol Chem. 1970 Nov 25;245(22):6237-9.
8
Isolation and partial characterization of reticulocyte factors M1 and M2.网织红细胞因子M1和M2的分离及部分特性分析
J Biol Chem. 1970 Nov 10;245(21):5553-9.
9
Ribosomal subunit exchange in Dictyostelium purpureum.紫柄盘基网柄菌中的核糖体亚基交换
J Cell Biol. 1970 Aug;46(2):428-30. doi: 10.1083/jcb.46.2.428.
10
Separation of two factors, M1 and M2, required for poly U dependent polypeptide synthesis by rabbit reticulocyte ribosomes at low magnesium ion concentration.在低镁离子浓度下，兔网织红细胞核糖体合成多聚 U 依赖性多肽所需的两种因子 M1 和 M2 的分离。
Biochem Biophys Res Commun. 1970 Feb 20;38(4):721-7. doi: 10.1016/0006-291x(70)90641-8.

一种来自兔网织红细胞的核糖体解离因子（氟化物-大肠杆菌核糖体-起始因子）。

A ribosome dissociation factor from rabbit reticulocytes (fluoride-E. coli ribosomes-initiation factors).

作者信息

Lubsen N H, Davis B D

出版信息

Proc Natl Acad Sci U S A. 1972 Feb;69(2):353-7. doi: 10.1073/pnas.69.2.353.

DOI:10.1073/pnas.69.2.353
PMID:4551141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC426456/
Abstract

A ribosome dissociation factor has been detected in an extract of ribosomal particles from rabbit reticulocytes. This factor dissociates free ribosomes from reticulocytes and also from Escherichia coli; it does not dissociate ribosomes complexed with peptidyl-tRNA and mRNA. The reaction appears to be stoichiometric rather than catalytic; it reaches completion in one minute at 37 degrees C, but is very slow at 0 degrees C, and it is antagonized and reversed by Mg(++). Reticulocyte dissociation factor thus closely resembles that from E. coli. However, the activity has been found primarily associated with the native large subunits rather than the small subunits in lysates.

摘要

在兔网织红细胞核糖体颗粒提取物中检测到一种核糖体解离因子。该因子可使网织红细胞以及大肠杆菌中的游离核糖体解离；但不会使与肽基 - tRNA和mRNA结合的核糖体解离。该反应似乎是化学计量的而非催化性的；在37℃下1分钟内反应完成，但在0℃时非常缓慢，并且Mg(++)可拮抗并逆转该反应。因此，网织红细胞解离因子与大肠杆菌的解离因子非常相似。然而，已发现该活性主要与裂解物中的天然大亚基相关，而非小亚基。