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格拉斯哥肺气肿的尸检研究

A necropsy study of pulmonary emphysema in Glasgow.

作者信息

Roberts G H, Scott K W

出版信息

Thorax. 1972 Jan;27(1):28-32. doi: 10.1136/thx.27.1.28.

Abstract

The incidence of pulmonary emphysema in a series of 50 necropsies on male subjects in Glasgow has been investigated. Emphysema was present in 37 lungs (74%) and found in more than trace amounts in 32 lungs (64%). These results are similar to those previously reported from London, Edinburgh, and Cardiff but emphysema in younger men appears to be more severe in Glasgow than in these other cities. Centrilobular emphysema was the commonest variety, found in 36 of the 50 lungs (72%); it was the only or predominant type in 17 (34%). Panlobular emphysema was found in 25 lungs (50%), but only in 5 (10%) was this the predominant or the only variety. In 15 cases (30%), significant amounts of both centrilobular and panlobular emphysema were present. Three methods were used to measure emphysema, including the recently introduced method which compares the severity of emphysma on paper-mounted large sections with standard charts arbitrarily graded according to severity. The method of scoring is quick and gave results comparable to those using Heard's method on the barium impregnated slice. It has the added advantage that paper-mounted sections, unlike barium-impregnated slices, are easily stored and thus provide a permanent record.

摘要

对格拉斯哥50例男性尸检病例中的肺气肿发病率进行了调查。37例肺部存在肺气肿(74%),32例肺部肺气肿含量超过微量(64%)。这些结果与之前伦敦、爱丁堡和加的夫报道的结果相似,但格拉斯哥年轻男性的肺气肿似乎比其他城市更为严重。小叶中心型肺气肿最为常见,50例肺部中有36例(72%);其中17例(34%)是唯一或主要的类型。全小叶型肺气肿见于25例肺部(50%),但只有5例(10%)是主要或唯一的类型。15例(30%)同时存在大量小叶中心型和全小叶型肺气肿。采用了三种方法来测量肺气肿,包括最近引入的一种方法,即将纸质大切片上的肺气肿严重程度与根据严重程度任意分级的标准图表进行比较。评分方法快速,结果与在钡浸渍切片上使用赫德方法的结果相当。它还有一个额外的优点,即与钡浸渍切片不同,纸质切片易于保存,因此能提供永久记录。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/136a/472454/ed2b9d88b4d1/thorax00121-0035-a.jpg

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