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大鼠胃表面上皮细胞的吞噬作用。

Phagocytosis of cells in the gastric surface epithelium of the rat.

作者信息

Morris G P, Harding R K

出版信息

Cell Tissue Res. 1979 Feb 28;196(3):449-54. doi: 10.1007/BF00234739.

DOI:10.1007/BF00234739
PMID:455388
Abstract

Gastric surface epithelial cells (SEC) from fed rats, from rats fasted for 16 h and from mucosae exposed in an ex-vivo chamber to 16 mM aspirin for 5 min were examined by transmission electron microscopy. SEC have the capability to phagocytose adjacent epithelial cells and parietal cells. Phagocytosis is rare in mucosae from fasted animals but common in fed animals or after brief exposure to aspirin. Phagocytic capabilities are not restricted to the progenitor zone but exist throughout the surface epithelium. Phagocytosis may provide a mechanism for the removal of damaged or senescent cells from the surface epithelium.

摘要

通过透射电子显微镜检查了来自喂食大鼠、禁食16小时的大鼠以及在体外腔室中暴露于16 mM阿司匹林5分钟的黏膜的胃表面上皮细胞(SEC)。SEC具有吞噬相邻上皮细胞和壁细胞的能力。在禁食动物的黏膜中吞噬作用很少见,但在喂食动物或短暂接触阿司匹林后很常见。吞噬能力不限于祖细胞区,而是存在于整个表面上皮中。吞噬作用可能为从表面上皮中清除受损或衰老细胞提供一种机制。

相似文献

1
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Cell Tissue Res. 1979 Feb 28;196(3):449-54. doi: 10.1007/BF00234739.
2
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本文引用的文献

1
Ultrastructural and cytochemical studies on karyolytic bodies in the epithelium of the duodenal crypts of whole body x-irradiated mice.对全身X射线照射小鼠十二指肠隐窝上皮中核溶解小体的超微结构和细胞化学研究。
Lab Invest. 1966 Oct;15(10):1528-43.
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Paneth and goblet cell renewal in mouse duodenal crypts.小鼠十二指肠隐窝中潘氏细胞和杯状细胞的更新
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Cell Tissue Res. 1985;239(2):343-7. doi: 10.1007/BF00218013.
小鼠小肠中四种主要上皮细胞类型的起源、分化和更新。V. 四种上皮细胞类型起源的统一理论。
Am J Anat. 1974 Dec;141(4):537-61. doi: 10.1002/aja.1001410407.
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[Electron microscopic findings in the epithelium of the small intestine and the endometrium of the mouse after colchicine administration].
Verh Dtsch Ges Pathol. 1967;51:401-6.
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Electronmicroscopic observations on the effects of orally administered aspirin and aspirin-bicarbonate mixtures on the development of gastric mucosal damage in the rat.关于口服阿司匹林及阿司匹林 - 碳酸氢盐混合物对大鼠胃黏膜损伤发展影响的电子显微镜观察
Gut. 1975 Jul;16(7):514-27. doi: 10.1136/gut.16.7.514.
6
Electron microscopic study of the repair of aspirin-induced gastric erosions.阿司匹林所致胃黏膜糜烂修复的电子显微镜研究
Am J Dig Dis. 1976 Jul;21(7):533-41. doi: 10.1007/BF01464759.
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Ultrastructural changes in the gastric mucosa following hemorrhagic shock in pigs.猪失血性休克后胃黏膜的超微结构变化
Circ Shock. 1977;4(1):13-25.
8
Cell loss from normal and stressed gastric mucosae of the rat. An ultrastructural analysis.大鼠正常及应激胃黏膜的细胞丢失。超微结构分析。
Gastroenterology. 1977 May;72(5 Pt 1):857-63.
9
Colonic epithelial cells and polymorphonuclear leukocytes in ulcerative colitis. An electron-microscopic study.溃疡性结肠炎中的结肠上皮细胞和多形核白细胞。一项电子显微镜研究。
Am J Dig Dis. 1975 Mar;20(3):236-52. doi: 10.1007/BF01070727.