单次低温“喷射”灌注肝脏保存法。
Liver preservation by single passage hypothermic "squirt" perfusion.
作者信息
Calne R Y, Dunn D C, Herbertson B M, Gordon E M, Bitter-Suermann H, Robson A J, Macdonald A S, Davis D R, Smith D P, Reitter F H, Webster L M
出版信息
Br Med J. 1972 Oct 21;4(5833):142-4. doi: 10.1136/bmj.4.5833.142.
A single passage, hypothermic, intermittent squirt perfusion of the pig's liver is described which has allowed preservation of porcine livers for up to 17 hours. After preservation, orthotopically allografted livers can maintain recipient animals in good health. If this technique can be applied to clinical liver transplantation it should be possible to move livers from one hospital to another in the same way that kidneys are transported. This should increase the availability of donor livers for transplantation and avoid the serious disadvantages of moving the sick recipient just before the operation to the hospital where the donor has died.
本文描述了一种对猪肝进行单次低温间歇性喷射灌注的方法，该方法可使猪肝保存长达17小时。保存后，原位同种异体移植的肝脏能够维持受体动物的健康状态。如果这项技术能够应用于临床肝移植，那么就有可能像运输肾脏一样，将肝脏从一家医院转移到另一家医院。这将增加可供移植的供体肝脏数量，并避免在手术前将患病受体转移到供体死亡医院所带来的严重弊端。
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