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通过冷灌注对犬类和人类肝脏进行6至18小时的保存。

Canine and human liver preservation for 6 to 18 hr by cold infusion.

作者信息

Benichou J, Halgrimson C G, Weil R, Koep L J, Starzl T E

出版信息

Transplantation. 1977 Dec;24(6):407-11. doi: 10.1097/00007890-197712000-00001.

Abstract

Forty-one dog livers were preserved with cold, lactated Ringer's, plasma, or intracellular (Collins) solutions. Consistent survival was obtained with all three solutions for 9 hr. After 18 hr, the plasma and Collins solutions permitted survival, with the Collins solution having a slight overall advantage. The method using Collins solution has been used to preserve seven human livers in Los Angeles, to transport the organs to Denver, and to transport them as orthotopic grafts from 6 hr, 45 min to 10 hr later.

摘要

41个狗肝脏分别用冷的乳酸林格氏液、血浆或细胞内液(柯林斯液)进行保存。这三种溶液均可使肝脏持续存活9小时。18小时后,血浆和柯林斯液仍能维持肝脏存活,柯林斯液总体上略占优势。在洛杉矶,采用柯林斯液保存法已成功保存了7个供体肝脏,将这些器官运往丹佛,并在6小时45分钟至10小时后作为原位移植物进行移植。

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本文引用的文献

3
Short term preservation of porcine livers.
J Surg Res. 1970 Feb;10(2):55-61. doi: 10.1016/0022-4804(70)90010-7.
5
Preservation of the porcine liver.猪肝的保存
Transplant Proc. 1974 Sep;6(3):289-94.
7
Kidney preservation for transportation. Initial perfusion and 30 hours' ice storage.
Lancet. 1969 Dec 6;2(7632):1219-22. doi: 10.1016/s0140-6736(69)90753-3.

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