渗透压摩尔浓度对大肠杆菌和奇异变形杆菌对青霉素反应的影响。
The effect of osmolality on the response of Escherichia coli and Proteus mirabilis to penicillins.
作者信息
Greenwood D, O'Grady F
出版信息
Br J Exp Pathol. 1972 Oct;53(5):457-64.
Abstract
The response of broth cultures of and to ampicillin was continuously monitored turbidometrically. The rapid lytic response which follows a few minutes after addition of the antibiotic as well as the later slow lysis of spheroplasts could be manipulated by altering the osmolality of the medium. A higher osmolality was found to be necessary to protect than and this explains the differential response of the 2 organisms that we have previously described.
摘要
对[具体细菌名称 1]和[具体细菌名称 2]的肉汤培养物对氨苄青霉素的反应进行了比浊法连续监测。添加抗生素后几分钟出现的快速裂解反应以及随后原生质球的缓慢裂解可通过改变培养基的渗透压来控制。发现保护[具体细菌名称 1]比[具体细菌名称 2]需要更高的渗透压，这解释了我们之前描述的这两种生物体的不同反应。
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本文引用的文献
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J Clin Pathol. 1964 Jan;17(1):69-74. doi: 10.1136/jcp.17.1.69.
2
A note on the use of a simple medium to determine the sensitivity to penicillin of Proteus species.关于使用一种简单培养基测定变形杆菌属对青霉素敏感性的说明。
J Med Lab Technol. 1960 Jul;17:184-6.
3
A comparison of the effects of ampicillin on Escherichia coli and proteus mirabilis.氨苄青霉素对大肠杆菌和奇异变形杆菌作用的比较。
J Med Microbiol. 1969 Nov 4;2(4):435-41. doi: 10.1099/00222615-2-4-435.
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Phys Med Biol. 1969 Oct;14(4):555-8. doi: 10.1088/0031-9155/14/4/302.
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