Crockett J K, Brownell G H
J Virol. 1972 Oct;10(4):737-45. doi: 10.1128/JVI.10.4.737-745.1972.
A stable phage-carrying strain of Nocardia erythropolis was isolated from an infection with the nocardiophage phiEC. Growth of the strain in phage-specific antiserum for 48 hr produced cured organisms at a frequency of about 0.5%. Spontaneous curing, determined by serial single-colony isolations, was less than 0.4%. The strain could not be infected by phage phiEC nor by a closely related phage, phiC, although the cells were able to adsorb these phages. In cell populations, a frequency of 2.5 x 10(-4) cells spontaneously induced. The growth rate of the strain was comparable to that of the uninfected wild-type N. erythropolis. Ultraviolet irradiation or treatment with mitomycin C induced the strain to produce larger numbers of phage. It was concluded that the isolated strain was lysogenic.
从红平红球菌被嗜诺卡氏菌噬菌体phiEC感染的样本中分离出了一株携带稳定噬菌体的菌株。该菌株在噬菌体特异性抗血清中培养48小时后，治愈的菌体出现频率约为0.5%。通过连续单菌落分离测定的自发治愈频率低于0.4%。尽管该菌株的细胞能够吸附噬菌体phiEC和密切相关的噬菌体phiC，但它不能被这两种噬菌体感染。在细胞群体中，自发诱导的频率为2.5×10⁻⁴个细胞。该菌株的生长速率与未感染的野生型红平红球菌相当。紫外线照射或丝裂霉素C处理可诱导该菌株产生更多噬菌体。得出的结论是，分离出的菌株是溶源性的。
