Melechen N E, Hudnik-Plevnik T A
Proc Natl Acad Sci U S A. 1972 Nov;69(11):3195-8. doi: 10.1073/pnas.69.11.3195.
Analyses of the time of recombination in bacteria infected with phage lambda and in spheroplasts infected with purified phage lambda DNA indicate a preponderance of recombination occurring before replication ("early recombination") after infection with tandem dimers formed in vitro compared to linear monomer DNA and phage infections. Among the early recombinants is a large fraction of cells that produces one recombinant type exclusively. Two suggestions are discussed-that a dimer-like molecule is the precursor of the recombinant progeny molecule and that one recombinant chromosome is the frequent or exclusive product of a recombinational event.
对感染噬菌体λ的细菌以及感染纯化的噬菌体λ DNA 的原生质体中重组时间的分析表明，与线性单体 DNA 和噬菌体感染相比，体外形成的串联二聚体感染后，重组主要发生在复制之前（“早期重组”）。在早期重组体中，很大一部分细胞只产生一种重组类型。文中讨论了两种观点——一种二聚体样分子是重组后代分子的前体，以及一条重组染色体是重组事件的常见或唯一产物。
