去势对CFW小鼠白色念珠菌性尿路感染的影响。
Influence of gonadectomy on Candida albicans urinary tract infection in CFW mice.
作者信息
Rifkind D, Frey J A
出版信息
Infect Immun. 1972 Mar;5(3):332-6. doi: 10.1128/iai.5.3.332-336.1972.
Abstract
Candida albicans appeared in the urine of approximately 80% of CFW mice of both sexes within 2 weeks after intraperitoneal inoculation. During a follow-up period of 10 weeks, candiduria tended to clear, but persisted in 37% of males as compared to only 16% in females. Autopsy kidney cultures yielded candida in 53% of males as compared to 25% of females. Urine cultures in both sexes when positive contained 10(3.5) to 10(4.5) candida/ml regardless of the outcome of the infection. Preinoculation gonadectomy in both sexes increased resistance to the infection but did not alter the quantitative aspects of candiduria.
摘要
白色念珠菌在腹腔接种后2周内出现在约80%的CFW雌雄小鼠尿液中。在10周的随访期内，念珠菌尿倾向于清除，但在37%的雄性小鼠中持续存在，而雌性小鼠中仅为16%。尸检肾脏培养显示，53%的雄性小鼠有念珠菌生长，而雌性小鼠为25%。无论感染结果如何，两性尿液培养阳性时每毫升含有10(3.5)至10(4.5)个念珠菌。两性在接种前进行性腺切除可增加对感染的抵抗力，但并未改变念珠菌尿的定量情况。
相似文献
1
Influence of gonadectomy on Candida albicans urinary tract infection in CFW mice.去势对CFW小鼠白色念珠菌性尿路感染的影响。
Infect Immun. 1972 Mar;5(3):332-6. doi: 10.1128/iai.5.3.332-336.1972.
2
Sex difference in antibody response of CFW mice to Candida albicans.CFW小鼠对白色念珠菌抗体反应的性别差异。
Infect Immun. 1972 May;5(5):695-8. doi: 10.1128/iai.5.5.695-698.1972.
3
[Candida urinary tract infection with special reference to ascending pyelonephritis].[念珠菌性尿路感染，特别提及上行性肾盂肾炎]
Hinyokika Kiyo. 1991 Sep;37(9):969-74.
4
Susceptibility to experimental Candida albicans urinary tract infection in the rat.大鼠对实验性白色念珠菌尿路感染的易感性。
J Infect Dis. 1987 May;155(5):841-6. doi: 10.1093/infdis/155.5.841.
5
Candida growth in urine cultures: a contemporary analysis of species and antifungal susceptibility profiles.尿培养中的念珠菌生长：菌种及抗真菌药敏谱的当代分析
QJM. 2016 May;109(5):325-9. doi: 10.1093/qjmed/hcv202. Epub 2015 Nov 4.
6
Prevalence of albicans and non-albicans candiduria in a Malaysian medical centre.马来西亚一家医疗中心白色念珠菌性和非白色念珠菌性念珠菌尿症的患病率。
J Pak Med Assoc. 2014 Dec;64(12):1375-9.
7
Yeasts isolated from nosocomial urinary infections: antifungal susceptibility and biofilm production.从医院获得性尿路感染中分离出的酵母菌：抗真菌药敏性和生物膜形成
Rev Iberoam Micol. 2014 Apr-Jun;31(2):104-8. doi: 10.1016/j.riam.2013.06.004. Epub 2013 Jun 25.
8
Detection of Candida casts in experimental renal candidiasis: implications for the diagnosis and pathogenesis of upper urinary tract infection.实验性肾念珠菌病中念珠菌管型的检测：对上尿路感染诊断和发病机制的意义
J Med Vet Mycol. 1994 Dec;32(6):415-26. doi: 10.1080/02681219480000571.
9
[The management of urinary candidiasis in cystectomized patients].
Actas Urol Esp. 1999 Jan;23(1):22-7.
10
Early identification of candiduria by polymerase chain reaction in high risk patients.
J Urol. 1996 Jul;156(1):154-6.
引用本文的文献
1
Sexual Dimorphism and Gender in Infectious Diseases.性二态性与传染病中的性别差异。
Front Immunol. 2021 Jul 22;12:698121. doi: 10.3389/fimmu.2021.698121. eCollection 2021.
2
Effect of testosterone and estrogen supplementation on the resistance to systemic infection in mice.睾酮和雌激素补充剂对小鼠全身感染抵抗力的影响。
Heliyon. 2020 Jul 12;6(7):e04437. doi: 10.1016/j.heliyon.2020.e04437. eCollection 2020 Jul.
3
Production and function of cytokines in natural and acquired immunity to Candida albicans infection.白色念珠菌感染天然免疫和获得性免疫中细胞因子的产生与功能
Microbiol Rev. 1995 Dec;59(4):646-72. doi: 10.1128/mr.59.4.646-672.1995.
4
Binding of Candida albicans yeast cells to mouse popliteal lymph node tissue is mediated by macrophages.白色念珠菌酵母细胞与小鼠腘淋巴结组织的结合是由巨噬细胞介导的。
Infect Immun. 1993 Aug;61(8):3244-9. doi: 10.1128/iai.61.8.3244-3249.1993.
5
Immunity to Candida albicans.对白假丝酵母菌的免疫力。
Microbiol Rev. 1980 Dec;44(4):660-82. doi: 10.1128/mr.44.4.660-682.1980.
6
Influence of gonadal factors on skin test reactivity of CFW mice to Candida albicans.性腺因素对CFW小鼠皮肤对白色念珠菌反应性的影响。
Infect Immun. 1973 Mar;7(3):322-8. doi: 10.1128/iai.7.3.322-328.1973.
7
Sex difference in susceptibility of mice to pneumococcus.小鼠对肺炎球菌易感性的性别差异。
Experientia. 1973 Mar 15;29(3):374-5. doi: 10.1007/BF01926540.
8
Enhanced immune responses in mice treated with penicillin-tetracycline or trimethoprim-sulfamethoxazole when colonized intragastrically with Candida albicans.当用白色念珠菌进行胃内定植时，用青霉素 - 四环素或甲氧苄啶 - 磺胺甲恶唑治疗的小鼠免疫反应增强。
Antimicrob Agents Chemother. 1987 May;31(5):691-7. doi: 10.1128/AAC.31.5.691.
9
Experimental Candida albicans infection in conventional mice and germfree rats.在普通小鼠和无菌大鼠中进行白色念珠菌感染实验。
Infect Immun. 1976 Jul;14(1):33-8. doi: 10.1128/iai.14.1.33-38.1976.
本文引用的文献
1
Steroids and serum complement in mice: influence of hydrocortisone, diethylstilbestrol, and testosterone.类固醇和血清补体在小鼠中的作用：氢化可的松、己烯雌酚和睾酮的影响。
Science. 1966 May 6;152(3723):782-3. doi: 10.1126/science.152.3723.782.
2
Effect of Estrogen and Other Steroids on MM Virus Infection in Mice.雌激素和其他类固醇对小鼠 MM 病毒感染的影响。
Infect Immun. 1970 Oct;2(4):426-30. doi: 10.1128/iai.2.4.426-430.1970.
3
SEX DIFFERENCES IN SUSCEPTIBILITY TO INFECTIONS.感染易感性中的性别差异。
Pediatrics. 1965 Jan;35:57-64.
4
THE EFFECT OF DIETHYLSTILBESTROL ON THE SUSCEPTIBILITY OF RATS TO HEMATOGENOUS PYELONEPHRITIS.己烯雌酚对大鼠血源性肾盂肾炎易感性的影响
J Clin Invest. 1964 Jun;43(6):1136-45. doi: 10.1172/JCI104998.
5
Effects of steroid sex hormones on immunological phenomena.类固醇性激素对免疫现象的影响。
Nature. 1963 Jun 1;198:902. doi: 10.1038/198902a0.
6
7
Enhancement of staphylococcal infection in mice by estrogens. I. Effect of the timing, quantity and quality of the hormone.雌激素增强小鼠葡萄球菌感染。I. 激素的时间、数量和质量的影响。
Ann Med Exp Biol Fenn. 1967;45(2):138-46.
8
Mouse complement: the effect of sex hormones and castration on two of the late-acting components.小鼠补体：性激素和去势对两种晚期作用成分的影响。
J Exp Med. 1967 Apr 1;125(4):657-72. doi: 10.1084/jem.125.4.657.
9
Effect of estrogen and progesterone on leukocyte glycogen and alkaline phosphatase in dogs.雌激素和孕酮对犬白细胞糖原及碱性磷酸酶的影响。
Proc Soc Exp Biol Med. 1969 Oct;132(1):193-4. doi: 10.3181/00379727-132-34178.
10
The influence of various hormones on the reticulo-endothelial system: endocrine control of body defense.各种激素对网状内皮系统的影响：机体防御的内分泌控制。
J Endocrinol. 1965 Nov;33(3):365-83. doi: 10.1677/joe.0.0330365.
Zotero 插件