去势对CFW小鼠白色念珠菌性尿路感染的影响。
Influence of gonadectomy on Candida albicans urinary tract infection in CFW mice.
作者信息
Rifkind D, Frey J A
出版信息
Infect Immun. 1972 Mar;5(3):332-6. doi: 10.1128/iai.5.3.332-336.1972.
Abstract
Candida albicans appeared in the urine of approximately 80% of CFW mice of both sexes within 2 weeks after intraperitoneal inoculation. During a follow-up period of 10 weeks, candiduria tended to clear, but persisted in 37% of males as compared to only 16% in females. Autopsy kidney cultures yielded candida in 53% of males as compared to 25% of females. Urine cultures in both sexes when positive contained 10(3.5) to 10(4.5) candida/ml regardless of the outcome of the infection. Preinoculation gonadectomy in both sexes increased resistance to the infection but did not alter the quantitative aspects of candiduria.
摘要
白色念珠菌在腹腔接种后2周内出现在约80%的CFW雌雄小鼠尿液中。在10周的随访期内，念珠菌尿倾向于清除，但在37%的雄性小鼠中持续存在，而雌性小鼠中仅为16%。尸检肾脏培养显示，53%的雄性小鼠有念珠菌生长，而雌性小鼠为25%。无论感染结果如何，两性尿液培养阳性时每毫升含有10(3.5)至10(4.5)个念珠菌。两性在接种前进行性腺切除可增加对感染的抵抗力，但并未改变念珠菌尿的定量情况。
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本文引用的文献
1
Steroids and serum complement in mice: influence of hydrocortisone, diethylstilbestrol, and testosterone.
Science. 1966 May 6;152(3723):782-3. doi: 10.1126/science.152.3723.782.
2
Effect of Estrogen and Other Steroids on MM Virus Infection in Mice.
Infect Immun. 1970 Oct;2(4):426-30. doi: 10.1128/iai.2.4.426-430.1970.
3
SEX DIFFERENCES IN SUSCEPTIBILITY TO INFECTIONS.
Pediatrics. 1965 Jan;35:57-64.
4
THE EFFECT OF DIETHYLSTILBESTROL ON THE SUSCEPTIBILITY OF RATS TO HEMATOGENOUS PYELONEPHRITIS.
J Clin Invest. 1964 Jun;43(6):1136-45. doi: 10.1172/JCI104998.
5
Effects of steroid sex hormones on immunological phenomena.
Nature. 1963 Jun 1;198:902. doi: 10.1038/198902a0.
6
Enhancement of staphylococcal infection in mice by estrogens. II. Effect of the inoculum size and the strain variation of bacteria and mice.
Ann Med Exp Biol Fenn. 1967;45(2):147-51.
7
Enhancement of staphylococcal infection in mice by estrogens. I. Effect of the timing, quantity and quality of the hormone.
Ann Med Exp Biol Fenn. 1967;45(2):138-46.
8
Mouse complement: the effect of sex hormones and castration on two of the late-acting components.
J Exp Med. 1967 Apr 1;125(4):657-72. doi: 10.1084/jem.125.4.657.
9
Effect of estrogen and progesterone on leukocyte glycogen and alkaline phosphatase in dogs.
Proc Soc Exp Biol Med. 1969 Oct;132(1):193-4. doi: 10.3181/00379727-132-34178.
10
The influence of various hormones on the reticulo-endothelial system: endocrine control of body defense.
J Endocrinol. 1965 Nov;33(3):365-83. doi: 10.1677/joe.0.0330365.
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