抗酸杆菌核糖体引发的迟发型超敏反应。I. 核糖体的分离、特性、迟发型超敏反应及特异性。
Delayed hypersensitivity reactions provoked by ribosomes from acid-fast bacilli. I. Ribosomal isolation, characterization, delayed hypersensitivity, and specificity.
作者信息
Baker R E, Hill W E, Larson C L
出版信息
Infect Immun. 1972 Sep;6(3):258-65. doi: 10.1128/iai.6.3.258-265.1972.
Abstract
Ribosomes and ribosomal subunits of Mycobacterium bovis (strain BCG) and M. smegmatis have been isolated and employed as skin test antigens in guinea pigs sensitized with homologous or heterologous organisms. Ribosomes and ribosomal subunits were found to be potent antigens for skin test purposes, and the 30S subunits were found to be more specific and active than the 50S subunits.
摘要
牛分枝杆菌（卡介苗菌株）和耻垢分枝杆菌的核糖体及核糖体亚基已被分离出来，并用作对同源或异源生物体致敏的豚鼠皮肤试验抗原。发现核糖体和核糖体亚基是用于皮肤试验的有效抗原，并且发现30S亚基比50S亚基更具特异性和活性。
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