Barkai A, Allweis C
J Lipid Res. 1972 Nov;13(6):725-32.
The effect of electrical stimulation of various hypothalamic regions on levels of plasma free fatty acids, glucose, triglycerides, and cholesterol was studied in fasted cats. Appreciable changes were observed in plasma free fatty acids and glucose but not in plasma triglycerides or cholesterol. These changes appeared to be dependent upon small differences in the placement of electrodes and could not be related to a distinct hypothalamic locus. The results indicate that there is a dissociation between hypothalamic neurons that may affect plasma glucose concentration and those that may affect the plasma free fatty acids. It is suggested that the hypothalamus of the cat contains neurons that may influence autonomic discharge to adipose tissue and thus affect the plasma free fatty acid level and other neurons that may influence autonomic discharge to the liver and thus affect glucose output into the circulation. The distribution of both types of neurons is not limited to a distinct region of the hypothalamus in cats.
在禁食的猫身上研究了电刺激下丘脑不同区域对血浆游离脂肪酸、葡萄糖、甘油三酯和胆固醇水平的影响。观察到血浆游离脂肪酸和葡萄糖有明显变化，但血浆甘油三酯或胆固醇没有变化。这些变化似乎取决于电极放置位置的微小差异，且与下丘脑的特定位点无关。结果表明，可能影响血浆葡萄糖浓度的下丘脑神经元与可能影响血浆游离脂肪酸的神经元之间存在分离。有人提出，猫的下丘脑含有可能影响向脂肪组织的自主神经放电从而影响血浆游离脂肪酸水平的神经元，以及可能影响向肝脏的自主神经放电从而影响葡萄糖进入循环的输出的其他神经元。在猫中，这两种类型神经元的分布并不局限于下丘脑的特定区域。
