• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

下丘脑内胰岛素生成区和胰岛素缺乏区的定位

Topographic localisation of insulinogenic and insulinoprival areas in the hypothalamus.

作者信息

Garg S K, Chhina G S, Singh B

出版信息

Experientia. 1978 Sep 15;34(9):1237-8. doi: 10.1007/BF01922980.

DOI:10.1007/BF01922980
PMID:102526
Abstract

Electrical stimulation of hypothalamic areas through stereotaxically implanted electrodes were carried out in conscious male rhesus monkeys. There was a significant increase in immunoreactive insulin (IRI) following laterla hypothalamus (LHA) stimulation. An opposite response was obtained from ventromedial hypothalamus (VMH). Thus, insulinogenic and insulinoprival responses were obtained from feeding and satiety, suggesting a significant role of insulin in the regulation of food intake.

摘要

通过立体定向植入电极对清醒雄性恒河猴的下丘脑区域进行电刺激。刺激下丘脑外侧区(LHA)后,免疫反应性胰岛素(IRI)显著增加。而刺激腹内侧下丘脑(VMH)则得到相反的反应。因此,从进食和饱腹感中分别获得了促胰岛素和胰岛素缺乏反应,这表明胰岛素在食物摄入调节中具有重要作用。

相似文献

1
Topographic localisation of insulinogenic and insulinoprival areas in the hypothalamus.下丘脑内胰岛素生成区和胰岛素缺乏区的定位
Experientia. 1978 Sep 15;34(9):1237-8. doi: 10.1007/BF01922980.
2
Sexual behavior in male rhesus monkeys elicited by electrical stimulation of preoptic and hypothalamic areas.通过电刺激视前区和下丘脑区域引发雄性恒河猴的性行为。
Brain Res. 1979 Nov 9;177(1):127-44. doi: 10.1016/0006-8993(79)90923-5.
3
[Electrophysiologic study of hypothalamo-neocortical connections in Macaca mulatta monkeys].
Zh Evol Biokhim Fiziol. 1978 Mar-Apr;14(2):140-3.
4
Feeding suppression elicited by electrical and chemical stimulations of monkey hypothalamus.电刺激和化学刺激猴子下丘脑引发的摄食抑制
Am J Physiol. 1992 Apr;262(4 Pt 2):R586-94. doi: 10.1152/ajpregu.1992.262.4.R586.
5
Prolactin release following electrical stimulation of the brain in ovarectomized and ovariectomized estrogen-treated rhesus monkeys.对切除卵巢的恒河猴以及切除卵巢并用雌激素处理的恒河猴进行脑部电刺激后催乳素的释放情况。
Endocrinology. 1977 Feb;100(2):325-30. doi: 10.1210/endo-100-2-325.
6
Biochemical changes on ventromedial hypothalamic stimulation in monkeys with streptozotocin diabetes.链脲佐菌素诱导糖尿病猕猴下丘脑腹内侧核刺激后的生化变化
Indian J Exp Biol. 1980 Mar;18(3):256-8.
7
Glucose and endocrine responses to hypothalamic electrical stimulation in rats.大鼠下丘脑电刺激后的葡萄糖及内分泌反应
Am J Physiol. 1982 Mar;242(3):R220-6. doi: 10.1152/ajpregu.1982.242.3.R220.
8
Synchronization of EEG activity of male Rhesus monkeys Macaca mulatta treated with ovocyclin.
Acta Neurobiol Exp (Wars). 1979;39(5):361-7.
9
Effects of estradiol-17beta on the induction of gonadotropin release by electrical stimulation of the hypothalamus in rhesus monkeys.
Endocrinology. 1977 Feb;100(2):314-24. doi: 10.1210/endo-100-2-314.
10
Enhancement of immunoreactive somatostatin release into hypophysial portal blood by electrical stimulation of the preoptic area in the rat.电刺激大鼠视前区增强免疫反应性生长抑素向垂体门脉血中的释放。
Endocrinology. 1979 Dec;105(6):1416-8. doi: 10.1210/endo-105-6-1416.

引用本文的文献

1
Central Mechanisms of Glucose Sensing and Counterregulation in Defense of Hypoglycemia.低血糖防御中葡萄糖感应和代偿的中枢机制。
Endocr Rev. 2019 Jun 1;40(3):768-788. doi: 10.1210/er.2018-00226.

本文引用的文献

1
Localization of a "feeding center" in the hypothalamus of the rat.大鼠下丘脑“摄食中枢”的定位
Proc Soc Exp Biol Med. 1951 Jun;77(2):323-4. doi: 10.3181/00379727-77-18766.
2
Blood sugar changes induced by electrical stimulation of the hypothalamus in cat.电刺激猫下丘脑引起的血糖变化
Indian J Med Res. 1955 Jan;43(1):123-7.
3
Hypothalamic control of the pituitary adrenocortical response to stress stimuli.下丘脑对垂体肾上腺皮质对应激刺激反应的控制。
Indian J Med Res. 1954 Apr;42(2):231-48.
4
Coated charcoal immunoassay of insulin.胰岛素的包被炭免疫测定法。
J Clin Endocrinol Metab. 1965 Oct;25(10):1375-84. doi: 10.1210/jcem-25-10-1375.
5
Stimulation of insulin release by a ventro-lateral hypothalamic factor.下丘脑腹外侧因子对胰岛素释放的刺激作用。
J Endocrinol. 1971 Nov;51(3):601-2. doi: 10.1677/joe.0.0510601.
6
Growth hormone and insulin levels in weanling rats with ventromedial hypothalamic lesions.腹内侧下丘脑损伤的断乳大鼠的生长激素和胰岛素水平
Endocrinology. 1968 Jun;82(6):1125-32. doi: 10.1210/endo-82-6-1125.
7
The location of the chemoreceptor controlling growth hormone secretion during hypoglycemia in primates.灵长类动物低血糖期间控制生长激素分泌的化学感受器的位置。
Endocrinology. 1972 Jul;91(1):217-26. doi: 10.1210/endo-91-1-217.
8
Hypothalamic stimulation of insulin release.下丘脑对胰岛素释放的刺激。
J Endocrinol. 1973 Sep;58(3):681-2. doi: 10.1677/joe.0.0580681.
9
Effect of electrical stimulation of the hypothalamus on plasma free fatty acid concentration in cats.下丘脑电刺激对猫血浆游离脂肪酸浓度的影响。
J Lipid Res. 1972 Nov;13(6):725-32.
10
Blood glucose, insulin, and free fatty acids after stimulation and lesions of the hypothalamus.下丘脑受到刺激和损伤后的血糖、胰岛素及游离脂肪酸水平。
Am J Physiol. 1972 Jun;222(6):1446-52. doi: 10.1152/ajplegacy.1972.222.6.1446.