Kuznik B I, Malezhik L P, Molchanova N L, Rusiaev V F
Fiziol Zh SSSR Im I M Sechenova. 1979 Mar;65(3):414-20.
The amount of procoagulative and fibrinolytic agents in cellular organoids was studied in the cat n. ischiadicus. All cellular fractions revealed high thromboplastic activity. Plasminogen, its activator, and proactivator were discovered in the ischiadic nerve. In dogs, the changes of functional state of nerves were accompanied by discharging of tissue thromboplastin and stimulators of fibrinolysis into the external medium with stimulaneous changes of intracellular contents of hemocoagulating factors. Thus, electric stimulation of the nerve intensified its thromboplastic activity, increased concentration of analogs of the plasma factors (II, VII, IX) and stimulation of fibrinolytic agents. The data obtained suggest presence of close enough interaction between the changes of functional condition of cells and dynamics of their procoagulative and fibrinolytic power.
在猫的坐骨神经中研究了细胞类器官中促凝剂和纤溶剂的含量。所有细胞组分均显示出高凝血活性。在坐骨神经中发现了纤溶酶原、其激活剂和前激活剂。在狗身上，神经功能状态的变化伴随着组织凝血活酶和纤溶刺激剂释放到外部介质中，同时血液凝固因子的细胞内含量也发生变化。因此，神经的电刺激增强了其凝血活性，增加了血浆因子（II、VII、IX）类似物的浓度，并刺激了纤溶剂。所获得的数据表明，细胞功能状态的变化与其促凝和纤溶能力的动态之间存在足够紧密的相互作用。
