Beamish M R, Jones P A, Trevett D, Evans I H, Jacobs A
Br J Cancer. 1972 Dec;26(6):444-52. doi: 10.1038/bjc.1972.61.
An evaluation of iron metabolism has been carried out in 23 untreated patients with Hodgkin's disease and 6 patients with other lymphomata. The reduction in red cell life span is related to the stage of the disease. There is an almost universal impairment of iron release from the reticuloendothelial system with a consequent sideropenia and failure of iron delivery to the bone marrow for erythropoiesis. This defect is found in all stages of the disease and is not related to systemic symptoms.
对23例未经治疗的霍奇金病患者和6例其他淋巴瘤患者进行了铁代谢评估。红细胞寿命的缩短与疾病分期有关。网状内皮系统铁释放几乎普遍受损，导致缺铁血症以及铁无法输送至骨髓用于红细胞生成。这种缺陷在疾病的各个阶段均有发现，且与全身症状无关。
