犬肾同种异体移植中超急性（加速二次）排斥反应的性质及肝素对排斥反应过程的影响。
Nature of hyperacute (accelerated second set) rejection in dog renal allografts and effects of heparin on rejection process.
作者信息
Amery A H, Pegrum G D, Risdon R A, Williams G
出版信息
Br Med J. 1973 Feb 24;1(5851):455-8. doi: 10.1136/bmj.1.5851.455.
Abstract
Renal allografts were exchanged between unrelated mongrel dogs after previous sensitization with skin and kidney grafts from the same donors. Rapid rejection of the renal allografts was associated with the accumulation of platelets and leucocytes in the peritubular and glomerular capillaries but fibrin deposition was not demonstrated.Heparin infusion delayed but did not prevent the rejection process.
摘要
在先前用来自相同供体的皮肤和肾脏移植进行致敏后，将肾同种异体移植物在不相关的杂种狗之间进行交换。肾同种异体移植物的快速排斥反应与血小板和白细胞在肾小管周围和肾小球毛细血管中的积聚有关，但未显示纤维蛋白沉积。肝素输注可延迟但不能阻止排斥过程。
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本文引用的文献
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The relationship between the antigens of skin and kidney of the dog.
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Intravascular coagulation (IVC) in human renal allograft rejection.人类肾移植排斥反应中的血管内凝血（IVC）
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