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用于移植的人类肾脏保存:使用金宝灌注机的初步结果。

Preservation of human kidneys for transplantation: preliminary results with a Gambro perfusion machine.

作者信息

Stephenson T P, O'Donoghue E P, Hendry W F, Wickham J E

出版信息

Br Med J. 1973 Feb 17;1(5850):379-81. doi: 10.1136/bmj.1.5850.379.

Abstract

Twenty-six human cadaveric kidneys have been preserved for up to 36 hours by continuous perfusion with 4.5% albumin solution on a Gambro machine. Of these, 20 kidneys were transplanted, and six were discarded owing to poor perfusion characteristics during storage. Immediate function was obtained with four kidneys, of which two had been preserved for over 30 hours.Satisfactory renal function has been obtained with 17 kidneys, and three kidneys were lost owing to rejection or technical complications. It is our experience that human kidneys can be successfully preserved for up to 36 hours by this technique.

摘要

通过在 Gambro 机器上用 4.5%白蛋白溶液持续灌注,26 个人类尸体肾脏已被保存长达 36 小时。其中,20 个肾脏进行了移植,6 个因储存期间灌注特性不佳而被丢弃。4 个肾脏获得了即时功能,其中 2 个已保存超过 30 小时。17 个肾脏获得了令人满意的肾功能,3 个肾脏因排斥反应或技术并发症而丢失。我们的经验是,通过这种技术人类肾脏可以成功保存长达 36 小时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31df/1588271/3e0b73ea6794/brmedj01543-0023-a.jpg

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