慢性支气管炎患者静脉注射后痰液中头孢西丁和头孢呋辛的浓度（作者译）
[Cefoxitin and cefuroxim concentrations after intravenous administration in sputum of patients with chronic bronchitis (author's transl)].
作者信息
Zimmermann I, Ruhe W, Ritzerfeld W, Ulmer W T
出版信息
Immun Infekt. 1979 Apr;7(2):52-6.
PMID:457189
Abstract
On 24 patients with chronic obstructive bronchitis the Cefuroxim and Cefoxitin concentrations in the sputum were investigated during 11 days after intravenous injections. The concentrations of Cefuroxim were above the minimal concentrations necessary to block growing of bacteria. Cefoxitin showed lower concentrations. Different pharmacokinetics for both of the test substances may be responsible for the different results.
摘要
对24例慢性阻塞性支气管炎患者静脉注射后11天内痰液中的头孢呋辛和头孢西丁浓度进行了研究。头孢呋辛的浓度高于抑制细菌生长所需的最低浓度。头孢西丁的浓度较低。两种受试物质不同的药代动力学可能导致了不同的结果。
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