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对浓核症病毒两种感染类型结构的研究。

Studies on the structure of the two infectious types of densonucleosis virus.

作者信息

Tijssen P, Kurstak E

出版信息

Intervirology. 1979;11(5):261-7. doi: 10.1159/000149043.

Abstract

No electrophoretic differences were detected between the nucleic acids of the two types of densonucleosis virus, DNV-I and DNV-II. Both virus types had similar isoelectric points. Although the viral proteins found in each type were identical, their stoichiometry differed. The localization of the structural protein, by labeling with periodate-oxidized glycoprotein, supported the hypothesis that 60 molecules of p49 aggregated into a dodecahedron (12 pentamers), whereas the two other proteins (p59 and p69) might have a stabilizing function and were localized on the outer surface of the p49 dodecahedron.

摘要

在两种浓核症病毒(DNV-I和DNV-II)的核酸之间未检测到电泳差异。两种病毒类型具有相似的等电点。尽管在每种类型中发现的病毒蛋白相同,但其化学计量不同。通过高碘酸盐氧化糖蛋白标记结构蛋白的定位,支持了以下假设:60个p49分子聚集成一个十二面体(12个五聚体),而另外两种蛋白(p59和p69)可能具有稳定功能,并定位在p49十二面体的外表面。

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