Seiler R J
J Am Vet Med Assoc. 1979 Jan 1;174(1):72-5.
Seventeen cases of colorectal polyps in the dog were seen at the Ontario Veterinary College over a 12-year period. The mean age of occurrence was 6.9 years, and males and females were almost equally affected. The Collie was the most frequently affected breed (4/17). The clinical signs were typically dyschezia, periodic intermittent diarrhea and melena, and rectal prolapse of the polyp. The histopatholic classifcation were hyperplastic polyp (1), papillary adenoma (1), tubular adenoma (4), papillotubular adenoma (10), and unclassified (1). Severe epithelial atypia, likely carcinoma in situ, was apparent in 5 of the papillotubular adenomas. Retrospective analysis of survival data after polypectomy suggested a good prognosis, but the results were inconclusive and it is possible that some of the polyps represented premalignant lesions. Large polyps (greater than 1 cm in diameter) frequently had marked epithelial atypia and were considered more likely to recur or to become malignant.
在12年的时间里，安大略兽医学院共诊治了17例犬结肠息肉病例。发病的平均年龄为6.9岁，雄性和雌性受影响的几率几乎相同。柯利犬是受影响最频繁的品种（4/17）。临床症状通常为排便困难、周期性间歇性腹泻和黑便，以及息肉性直肠脱垂。组织病理学分类为增生性息肉（1例）、乳头状腺瘤（1例）、管状腺瘤（4例）、乳头管状腺瘤（10例）和未分类（1例）。在10例乳头管状腺瘤中，有5例出现严重上皮异型增生，可能为原位癌。息肉切除术后生存数据的回顾性分析表明预后良好，但结果尚无定论，一些息肉可能代表癌前病变。大息肉（直径大于1厘米）常伴有明显的上皮异型增生，被认为更有可能复发或恶变。
