Slabyj B M, Panos C
J Bacteriol. 1973 Jun;114(3):934-42. doi: 10.1128/jb.114.3.934-942.1973.
A stabilized L-form of Streptococcus pyogenes continues to synthesize glycerol teichoic acid. This polymer was obtained from S. pyogenes and its L-form, treated in identical fashion, and compared. Highly purified glycerol teichoic acid from only the L-form was found to be devoid of d-alanine and to have a shorter chain length. Otherwise, the glycerol teichoic acid from these two organisms was found to be a 1,3-phosphodiester-linked glycerophosphate polymer substituted with d-glucose. Evidence is presented that most, if not all, of the glycerol teichoic acid in this streptococcus lies between the wall and membrane. A possible need for the continued synthesis of a minute amount of glycerol teichoic acid by this L-form for survival is discussed in terms of the known function of teichoic acids in bacteria.
化脓性链球菌的稳定L型持续合成甘油磷壁酸。这种聚合物是从化脓性链球菌及其L型中以相同方式处理后获得并进行比较的。结果发现,仅来自L型的高度纯化的甘油磷壁酸不含D-丙氨酸且链长较短。否则,发现这两种生物体的甘油磷壁酸是一种由D-葡萄糖取代的1,3-磷酸二酯连接的甘油磷酸聚合物。有证据表明,这种链球菌中大部分(如果不是全部)甘油磷壁酸位于细胞壁和细胞膜之间。根据磷壁酸在细菌中的已知功能,讨论了这种L型为生存而持续合成微量甘油磷壁酸的可能需求。