Dilke T F, Burry H C, Grahame R
Br Med J. 1973 Jun 16;2(5867):635-7. doi: 10.1136/bmj.2.5867.635.
The effect of extradural corticosteroid injection in patients with nerve root compression syndromes associated with degenerative disease of the lumbar intervertebral discs was assessed in a double-blind controlled trial on 100 consecutive inpatients assigned by random allocation to treatment and control groups. Assessment during admission and at three months revealed statistically highly significant differences in respect of relief of pain and resumption of normal occupation in favour of the group treated by extradural injection. This treatment seems to be a valuable adjunct to the management of lumbar nerve root compression syndromes associated with degenerative disc disease.
在一项双盲对照试验中,对100例因腰椎间盘退变疾病导致神经根压迫综合征的连续住院患者进行随机分组,分别进入治疗组和对照组,评估硬膜外注射皮质类固醇的效果。入院时及三个月后的评估显示,在疼痛缓解和恢复正常工作方面,硬膜外注射治疗组具有统计学上的高度显著差异。这种治疗方法似乎是与退行性椎间盘疾病相关的腰神经根压迫综合征治疗中的一种有价值的辅助手段。