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在淋巴细胞转化试验中使用抗原混合物。

The use of an antigen-cocktail in the lymphocyte transformation test.

作者信息

Leguit P, Meinesz A, Huismans L, Eijsvoagel V P

出版信息

Clin Exp Immunol. 1973 May;14(1):149-52.

Abstract

A mixture was composed consisting of PPD, Varidase, Trychophyton-antigen, mumps-antigen and Candida-antigen. The reactivity to each antigen was tested and the response to the cocktail was found to reflect the sum of the effects of the anamnestic response to each antigen separately with a maximum of about the PHA-responsiveness. A group of twenty-five individuals showed an anamnestic response to at least two of the components of the antigen mixture. The cocktail as described may be useful in testing the cellular anamnestic response to antigens in patients who have a very low number of lymphocytes in their peripheral blood, such as patients with immune deficiencies and thermal injuries.

摘要

将PPD、链激酶-链道酶、毛癣菌抗原、腮腺炎抗原和念珠菌抗原混合制成一种混合物。检测了对每种抗原的反应性,发现对该混合抗原的反应反映了对每种抗原的回忆反应效应之和,最大反应约为PHA反应性。一组25名个体对该抗原混合物的至少两种成分表现出回忆反应。所述的这种混合抗原在检测外周血淋巴细胞数量非常少的患者(如免疫缺陷患者和热损伤患者)对抗原的细胞回忆反应方面可能有用。

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