Haines D E, Rubertone J A
J Comp Neurol. 1979 Aug 1;186(3):321-41. doi: 10.1002/cne.901860303.
The organization of corticonuclear fibers from lobule V of the anterior lobe of the lesser bushbaby, Galago senegalensis, was studied utilizing the Fink and Heimer ('67) method. Corticonuclear fibers of lobule V are ipsilateral, topographically arranged in their trajectory into the deep cerebellar nuclei and organized into six identifiable zones. No evidence is seen to support the contention that these fibers may project diffusely into the cerebellar nuclei, either in a rostro-caudal or medio-lateral sequence, or that they may project to any of the contralateral nuclei. Lesions in lateral lobule V cortex produce degeneration in rostroventral magnocellular NL. No debris is seen in pavicellular NL and no degenerated axons enter the NIA, NIP or NM. The terminal field in the NL is roughly pyramid shaped with the base being located at the periphery of the nucleus and the apex directed toward the hilus. Based on the totality of its efferent projections the intermediate cortex (IC) of lobule V is a relatively wide region which is divisible into three separate areas. Lateral portions of the IC project heavily into the lateral NIA and send a sparse number of fibers into the NIP. The middle area of the IC sends fibers almost exclusively to a bifid terminal field located in the NIP. From this area of cortex no degenerated fibers enter either the NL or NM and only extremely sparse amounts od debris are seen in rostrolateral NIA. Following damage to medial regions of IC degeneration is seen primarily in medial portions of the NIA and in the juxtarestiform body, if the lesion involves the lateral portions of the vermal cortex. These three regions of the IC, identified here based on the arrangement of their corticonuclear fibers represent the cortical correlates of compartments C1, C2 and C3 (of Voogd, '69). Lesions involving the lateral aspect of the vermal cortex produce degeneration in the vestibular complex, primarily its lateral nucleus, and in the NIP. These observations may represent a subdivision of this area, a fact previously reported in the cat (Oscarsson and Sjölund, '77a). The medial portions of the vermal cortex project primarily to rostrodorsal NM. The results of this study provide data concerning the arrangement of zones in anterior lobe cortex of a primate. Due to the fact that differential projections into magnocellular versus parvicellular NL were not seen, the lateral cortex is designated only as zone D. The IC contains, from lateral to medial, zones C3, C2 and C1. The lateral edge of the vermal cortex is designated zone B, although it is recognized that subdivisions of this area may exist (Oscarsson and Sjölund, '77a) while zone A is the more medial area of vermal cortex. These zone designations represent those portions of cortex which overlie previously identified compartments (Voogd, '69) in the subcortical white matter.
利用芬克和海默（1967年）的方法，对塞内加尔婴猴前叶小叶V的皮质核纤维组织进行了研究。小叶V的皮质核纤维是同侧的，在其进入小脑深部核团的轨迹中按地形排列，并组织成六个可识别的区域。没有证据支持这些纤维可能以头尾或中外侧顺序扩散投射到小脑核团，或者它们可能投射到任何对侧核团的观点。外侧小叶V皮质的损伤会导致嘴腹侧大细胞性外侧核的变性。在小细胞性外侧核中未见到碎片，也没有变性轴突进入下橄榄核主核、下橄榄核背侧副核或内侧副橄榄核。外侧核中的终末场大致呈金字塔形，底部位于核的周边，顶部指向门。基于其传出投射的总体情况，小叶V的中间皮质是一个相对较宽的区域，可分为三个独立的区域。中间皮质的外侧部分大量投射到外侧下橄榄核主核，并向背侧副橄榄核发送少量纤维。中间皮质的中间区域几乎只向位于背侧副橄榄核的一个双歧终末场发送纤维。从这个皮质区域没有变性纤维进入外侧核或内侧副橄榄核，并且仅在嘴外侧下橄榄核主核中看到极少的碎片。中间皮质内侧区域受损后，主要在外侧下橄榄核主核的内侧部分和近绳状体中出现变性，如果损伤涉及蚓部皮质的外侧部分。这里根据其皮质核纤维的排列确定的中间皮质的这三个区域代表了C1、C2和C3区（沃格德，1969年）的皮质对应物。涉及蚓部皮质外侧的损伤会导致前庭复合体，主要是其外侧核，以及背侧副橄榄核的变性。这些观察结果可能代表了该区域的一个细分，这一事实先前在猫中已有报道（奥斯卡松和舍隆德，1977a）。蚓部皮质的内侧部分主要投射到嘴背侧内侧副橄榄核。这项研究的结果提供了有关灵长类动物前叶皮质区域排列的数据。由于未观察到向大细胞性外侧核与小细胞性外侧核的差异投射现象，外侧皮质仅被指定为D区。中间皮质从外侧到内侧包含C3、C2和C1区。蚓部皮质的外侧边缘被指定为B区，尽管人们认识到该区域可能存在细分（奥斯卡松和舍隆德，1977a），而A区是蚓部皮质更内侧的区域。这些区域指定代表了皮质中覆盖先前在皮质下白质中确定的分区（沃格德，1969年）的那些部分。
