Bedigian H G, Sevoian M
Infect Immun. 1973 Sep;8(3):482-7. doi: 10.1128/iai.8.3.482-487.1973.
Cell-bound and cell-free herpesvirus of turkeys infected and replicated in guinea pig cell cultures as evidenced by cytopathic effects, intranuclear inclusions, and the presence of herpesvirus particles as seen by electron microscopy were studied in this investigation. Further evidence for the replication of herpesvirus of turkeys in cell cultures was determined by serum neutralization, complement fixation, and the fluorescent antibody tests.
本研究对火鸡疱疹病毒的细胞结合型和游离型在豚鼠细胞培养物中的感染和复制情况进行了研究。细胞病变效应、核内包涵体以及通过电子显微镜观察到的疱疹病毒颗粒均证明其能够在豚鼠细胞培养物中感染和复制。通过血清中和试验、补体结合试验和荧光抗体试验进一步确定了火鸡疱疹病毒在细胞培养物中的复制情况。