Willis A T, Bullen C L, Williams K, Fagg C G, Bourne A, Vignon M
Br Med J. 1973 Oct 13;4(5884):67-72. doi: 10.1136/bmj.4.5884.67.
The increased susceptibility of infants fed on cows' milk preparations has been attributed, at least in part, to differences in the nature of the large-bowel content-owing to the acidity of the faeces and their high content of Lactobacillus bifidus. In an attempt to mimic these features of the breastfed infant in one who is fed artificially, a breast milk substitute was devised which resembles breast milk in several important ways. When this material was fed to newborn infants the faeces developed the characteristics of those of the breast-fed child.
食用牛奶制品的婴儿易感性增加,至少部分原因是大肠内容物性质的差异——这归因于粪便的酸度及其高含量的双歧杆菌。为了在人工喂养的婴儿中模拟母乳喂养婴儿的这些特征,设计了一种在几个重要方面类似于母乳的母乳替代品。当将这种物质喂给新生儿时,粪便呈现出母乳喂养婴儿粪便的特征。