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多发性骨髓瘤：在看似化疗成功的过程中发生浆细胞肉瘤。

Multiple myeloma: development of plasma cell sarcoma during apparently successful chemotherapy.

作者信息

Holt J M, Robb-Smith A H

出版信息

J Clin Pathol. 1973 Sep;26(9):649-59. doi: 10.1136/jcp.26.9.649.

DOI:10.1136/jcp.26.9.649
PMID:4584727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC477846/
Abstract

Three patients with multiple myeloma who developed a plasma cell sarcoma during apparently successful chemothapy are described. It is postulated that the chemotherapy induced the sarcomatous change.

摘要

本文描述了3例多发性骨髓瘤患者，他们在看似成功的化疗期间发生了浆细胞肉瘤。据推测，化疗诱发了肉瘤样改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/7d97efb45cc7/jclinpath00119-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/76302a5e3814/jclinpath00119-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/b3c37146d6a2/jclinpath00119-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/485b3d131576/jclinpath00119-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/c56350811fc4/jclinpath00119-0015-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/79d51afe5309/jclinpath00119-0015-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/7fa6a9bb2db3/jclinpath00119-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/4505934c6acb/jclinpath00119-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/7d97efb45cc7/jclinpath00119-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/76302a5e3814/jclinpath00119-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/b3c37146d6a2/jclinpath00119-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/485b3d131576/jclinpath00119-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/c56350811fc4/jclinpath00119-0015-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/79d51afe5309/jclinpath00119-0015-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/7fa6a9bb2db3/jclinpath00119-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/4505934c6acb/jclinpath00119-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/359b/477846/7d97efb45cc7/jclinpath00119-0018-a.jpg

相似文献

1
Multiple myeloma: development of plasma cell sarcoma during apparently successful chemotherapy.多发性骨髓瘤：在看似化疗成功的过程中发生浆细胞肉瘤。
J Clin Pathol. 1973 Sep;26(9):649-59. doi: 10.1136/jcp.26.9.649.
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Multiple myeloma--development of alternative malignancy following successful chemotherapy.多发性骨髓瘤——化疗成功后发生的继发性恶性肿瘤
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[A case of Bence-Jones protein-lambda positive multiple myeloma complicated by abnormal plasma cells in pleural effusion].1例本-周蛋白λ阳性多发性骨髓瘤合并胸腔积液中异常浆细胞
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引用本文的文献

1
Anaplastic myeloma: a morphologic diagnostic dilemma.间变性骨髓瘤：一种形态学诊断难题。
Indian J Hematol Blood Transfus. 2008 Dec;24(4):188-9. doi: 10.1007/s12288-008-0046-3. Epub 2009 Jan 11.
2
The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique.使用免疫过氧化物酶技术对多发性骨髓瘤及相关病症的福尔马林 - 石蜡切片中的细胞内免疫球蛋白进行免疫组织学检测。
Clin Exp Immunol. 1974 Nov;18(3):417-29.
3
Identification of malignant plasma cell precursors in the bone marrow of multiple myeloma.

本文引用的文献

1
A case of acute plasma-cell leukemia supporting the concept of unity of plasmacellular neoplasia.一例支持浆细胞性肿瘤统一性概念的急性浆细胞白血病病例。
Cancer. 1952 May;5(3):514-20. doi: 10.1002/1097-0142(195205)5:3<514::aid-cncr2820050311>3.0.co;2-b.
2
Extramedullary lesions in multiple myeloma; review of literature and pathologic studies.多发性骨髓瘤的髓外病变；文献综述与病理研究
AMA Arch Pathol. 1952 Mar;53(3):262-72.
3
Soft-tissue involvement in multiple myelomatosis.
Br J Surg. 1952 Jan;39(156):361-4. doi: 10.1002/bjs.18003915623.
多发性骨髓瘤患者骨髓中恶性浆细胞前体的鉴定
J Clin Invest. 1985 Sep;76(3):1243-51. doi: 10.1172/JCI112080.
4
Multiple myeloma; lesions of the extra-osseous hematopoietic system.多发性骨髓瘤；骨外造血系统病变
Am J Clin Pathol. 1950 Oct;20(10):934-45. doi: 10.1093/ajcp/20.10.934.
5
Plasma cell myeloma; a clinical, pathologic and roentgenologic review of 90 cases.浆细胞骨髓瘤；90例临床、病理及X线回顾
Am J Clin Pathol. 1955 Aug;25(8):849-88. doi: 10.1093/ajcp/25.8.849.
6
[ON UNUSUAL COURSES IN HEMOBLASTOSES].[论成血细胞增多症的异常病程]
Beitr Pathol Anat. 1964 Jun;130:51-68.
7
MELPHALAN THERAPY IN MYELOMATOSIS.美法仑治疗骨髓瘤
Br Med J. 1964 Apr 4;1(5387):859-65. doi: 10.1136/bmj.1.5387.859.
8
[Multiple plasmocytoma with transition into giant cell reticulum cell sarcoma].[多发性浆细胞瘤转变为巨细胞网状细胞肉瘤]
Wien Klin Wochenschr. 1961 Jul 7;73:473-6.
9
Myelomatosis.骨髓瘤病
Lancet. 1961 Feb 4;1(7171):239-45. doi: 10.1016/s0140-6736(61)91420-9.
10
[Myeloma with plasmocytic pleural effusion].[伴有浆细胞性胸腔积液的骨髓瘤]
Acta Haematol. 1957 Dec;18(6):403-13. doi: 10.1159/000205353.